OBJECTIVE Therapeutic footwear for diabetic foot patients aims to reduce the risk of ulceration by relieving mechanical pressure on the foot. However, footwear efficacy is generally not assessed in clinical practice. The purpose of this study was to assess the value of in-shoe plantar pressure analysis to evaluate and optimize the pressure-reducing effects of diabetic therapeutic footwear. RE...

Introduction: Wound cleansing remains a corner stone in the management of diabetic foot ulcer. Hydrogen Peroxide (H2O2) and Povidone Iodine are topical antimicrobial agents but known to be toxic to cells involved in the wound healing cascade. The biggest challenge for the physicians and nurses is searching for a safe, noncytotoxic and effective wound cleansing as Hypochlorous acid (HOCL). This ...

RATIONALE Acral lentiginous melanoma (AML) does not exhibit the classic signs of malignant melanoma. ALM is frequently misdiagnosed because of its unusual sites and atypical clinical morphologies, which lead to poor prognosis. PATIENT CONCERNS A female patient aged 78 years was presented to our center with two ulcers on her right foot. Diabetic foot ulcer was considered as the primary diagnos...

Persons with diabetes mellitus (DM) and peripheral neuropathy are at high risk for skin breakdown due to unnoticed excessive pressures to the plantar foot during walking. We developed methods that combined spiral x-ray computed tomography (SXCT) imaging and plantar pressure analysis to quantify internal foot structure and external pressure during plantar loading. Methods were tested using a sub...

Diabetes affects roughly 537 million people in the world, and it is predicted to reach 783 by 2045. Diabetic Foot Ulcer (DFU) a major issue with diabetes that may lead lower limb amputation. The rapid evolution of DFU demands immediate intervention prevent terrible consequences amputation related complications.This research introduces novel approach utilizing deep neural networks machine learni...

Nonhealing diabetic foot ulcers (DFUs) are a common and costly complication of diabetes. Microbial burden, or "bioburden," is believed to underlie delayed healing, although little is known of those clinical factors that may influence microbial load, diversity, and/or pathogenicity. We profiled the microbiomes of neuropathic nonischemic DFUs without clinical evidence of infection in 52 individua...

Diabetic Foot Ulcer (DFU) is a complication of Diabetes Mellitus (DM), which major health problem throughout the world with high recurrence rate. It estimated that approximately 40% patients have within one year ulcer healing, nearly 60% three years, and 65% five years. One efforts to prevent DFU can be made foot care preceded by knowledge care. This study aimed compare before after being given...

OBJECTIVE To compare the effectiveness of different types of footwear insoles in the diabetic neuropathic foot. RESEARCH DESIGN AND METHODS A sample of 241 consecutive diabetic patients (158 men and 83 women, age 57.5 +/- 9.6 years [mean +/- SD], and mean duration of diabetes 12.3 +/- 7.2 years) attending the foot clinic with previous foot ulceration and those considered at high risk of foot ...