Natural products such as plant extracts and complex microbial secondary metabolites have recently attracted the attention of scientific world for their potential use as drugs for treating chronic diseases such as Type II diabetes. Non-Insulin-Dependent Diabetes Mellitus (NIDDM) or Type II diabetes has complicated basis and has various treatment options, each targeting different mechanism of act...

Background: Angiotensin I converting enzyme (ACE) is a Zinc metalloproteinase, converts Ang-I to Ang- II, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. Objective: To investigate the relationship between ACE I/D polymorphism and type 2 diabetes in 261 Iranian casecontrol pairs. Methods: 170 patients (85 type 2 diabetics with nephropathy a...

This study knew that comparing type 2 diabetes mellitus and some pro-inflammatory immune factors, IL-6 CRP clarified the higher glucose their relationship in stimulating these factors. Type II mellitus, elevated incidence of disease, IL6 II, absence substrates run on blood glucose.

Background: Diabetes mellitus is the most prevailing non- communicable diseases worldwide. It main reason of morbidity and mortality. Cognitive dysfunction one major complications associated with diabetes. a risk factor for cognitive decline as duration diabetes progress if accompanied by hypoglycemic attacks. Aim: To determine frequency dementia in patients suffering from type II mellitus. Stu...

One prevailing point of view is that many individuals with established type II diabetes have gone through years of impairment of glucose tolerance and hyperinsulinism before the appearance of fasting hyperglycemia (1,2). Peripheral insulin resistance plus a pancreatic p-cell insulin secretory defect presumably wage a battle over the years that results ultimately in clinically apparent type II d...

Both insulin resistance and insulin concentrations correlate with blood pressure in nondiabetic subjects, but there is no consensus on these relations in subjects with non-insulin-dependent diabetes, perhaps because of the use of nonspecific insulin assays and clinic blood pressure measurement. Therefore, we have investigated the relation between ambulatory blood pressure, insulin sensitivity (...