estrogen might play an important role in the pathogenesis of diabetes mellitus type 2. estrogens inhibit diabetes via distinct mechanisms particularly by reducing both hyperglycemia and plasma insulin levels. estrogen exerts its physiological effects mainly through estrogen receptors including α and β types. estrogen receptors are found in many tissues that participate in the pathogenesis of ty...

abstract objective: diabetes mellitus is the most common metabolic disease. one of the most common problems in diabetic patients is atherosclerotic cardiovascular disease which is induced by hyperlipidemia. impaired lipid metabolism resulting from uncontrolled hyperglycemia has been implicated in cardiovascular complications in diabetic patients. also, glycated hemoglobin (hba1c) has been regar...

background chronic renal failure is an important and common complication of diabetes mellitus; hence, renal transplantation is a frequent and the acceptable treatment in patients with diabetic nephropathy requiring renal replacement therapy. on the other hand, renal transplantation and its conventional treatment can lead to increased diabetes outbreak in normoglycemic recipients. also, uncontro...

background: gestational diabetes mellitus (gdm) is a common obstetrical complication with both maternal and fetal side effects.objective: this study was performed to determine the complications in neonates of mothers with gdm receiving insulin vs. dietary regimen.materials and methods: in this prospective cohort study, 140 neonates of mothers with gdm attending javaheri hospital of azad univers...

background: diabetes is one of the major concerns in the third millennium; affecting more people every day. the prevalence of this disease in iran is reported to be high (about 7.7%). the most important method to control this disease and prevent its complications from happening is self-care. according to various studies, this method has not found its appropriate place among patients with diabet...

background and aims. the aim of this study was to establish a relationship between salivary glucose levels and candida carriage rate in type 2 diabetes mellitus patients and assess the growth characteristics and acid production of candida in glucose-supplemented saliva. materials and methods. a total of 90 subjects, 30 with controlled type 2 diabetes, 30 with uncontrolled type 2 diabetes and 30...

backgrounds : new- onset diabetes after transplantation (nodat) is a serious complication which runs the risk of infections, morbidity and mortality. older age, male sex, immunosuppressive agents and hepatitis c are reported as risk factors. the focus of this research is evaluating some demographic and clinical factors in development of nodat in hepatic transplanted patients. this study aims to...

objective: as the aqueous extract of capparis spinosa (cs) possess antidiabetic effect, he present study aims to reveal the possible  mechanism of action of cs in diabetic mice.materials and methods: both single and repeated oral administrations of aqueous extract of cs were performed in multi-low dose streptozotocin-induced (mlds) diabetic mice. euglycemic hyperinsulinemic clamp was used in as...