Introduction The use of vemurafenib in melanoma has improved the survival of patients; however, it is associated with skin toxicities. Aim To assess skin toxicities by dermoscopy in patients treated with vemurafenib. Material and methods Eight patients with BRAF V600 mutation positive metastatic melanoma were examined dermoscopically during vemurafenib treatment. All skin lesions occurring ...

OBJECTIVES Malignant melanoma has high morbidity and mortality rates. Early diagnosis improves prognosis. Clinical prediction rules (CPRs) can be used to stratify patients with symptoms of suspected malignant melanoma to improve early diagnosis. We conducted a systematic review of CPRs for melanoma diagnosis in ambulatory care. DESIGN Systematic review. DATA SOURCES A comprehensive search o...

Intense Pulsed Light (IPL) is a broadband visible light emitted from a non-coherent, filtered flashlamp. IPL sources emit light in the 500-1200 nm range and allow treatment of vascular and melanocytic lesions, and also hair removal. Different cutoff filters can be used to narrow the spectrum to target specific structures. 1 We report significant changes observed in two nevi after hair removal t...

The dermatoscopy is a technique used for dermatologists as a diagnostic tool and also to monitor the response to treatments. Although this non-invasive imaging set has been used over decades, new applications have arisen such as preoperative evaluation of tumor margins, monitoring the response of topical treatments and post-treatment follow-up. In this work, I comment on the latest articles reg...

Richard Marchell, MD; Ashfaq A. Marghoob, MD; Ralph P. Braun, MD; Giuseppe Argenziano, MD; Departments of Dermatology, Stony Brook University Hospital, Stony Brook, NY (Dr Marchell), University Hospital Geneva, Geneva, Switzerland (Dr Braun), and Second University of Naples, Naples, Italy (Dr Argenziano); and the Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, NY (Dr Marg...

Irritated hyperhidrotic soles with multiple small pits are pathognomonic for pitted keratolysis (PK). Here we show the dermatoscopic view of typical pits that can ensure the diagnosis. PK is a plantar infection caused by Gram-positive bacteria, particularly Corynebacterium. Increases in skin surface pH, hyperhidrosis, and prolonged occlusion allow these bacteria to proliferate. The diagnosis is...

The lack of effective therapies for patients with advanced melanoma establishes an early recognition as the aim of clinical and dermoscopic examination, which is the most important factor for improving patient survival and decreases the treatment and management costs. Melanoma in situ is the earliest stage of melanoma. The features of early melanomas, especially in those lesions smaller than 3m...

5. Van Esso DL. Los padres frente a la vacunación. Vacunas. 2010;11:133--4. 6. Jiménez Gómez N, Ballester Martínez MA, Alcántara González J, Jaén Olasolo P. Koplik spots as a diagnostic clue in a case of measles. Med Clin (Barc). 2012;139:560. 7. Lefebvre N, Camuset G, Bui E, Christmann D, Hansmann Y. Koplik spots: a clinical sign with epidemiological implications for measles control. Dermatolo...

Pediculosis BLOCKINpubis BLOCKIN(PP) BLOCKINis BLOCKINinfestation BLOCKINwith BLOCKINpubic lice of the species Phthirus pubis. There are no ratial differences in its incidence and the infestation is generally common (1). Direct contact is the BLOCKINprimary BLOCKINsource BLOCKINof BLOCKINtransmission. BLOCKINIn BLOCKINadults, BLOCKINPP most frequently occurs as a sexually transmitted disease (S...

Chromoblastomycosis is a chronic cutaneous fungal infection commonly caused by Fonsacea and Cladophialophora spp. Dermoscopy is a non-invasive, real-time diagnostic tool for rapid bedside diagnosis of various inflammatory and non-inflammatory disorders and can be an excellent modality for evaluation of cutaneous mycosis, for which it shows characteristic brown dots, crust, scales and yellow ora...