OBJECTIVE To identify moderators of synchrony of change between depression severity and disability. METHOD From a large cohort study with 2 years of follow-up, patients with major depressive disorder at baseline who decreased at least 25% in depression severity after 2 years (n = 245) were selected. We measured overall and domain-specific disability at baseline, and at 1- and 2-year follow-up...

BACKGROUND Hand eczema is a disease frequently observed in dermatological practice. This condition has negative emotional, social, and psychological effects due to its impact on daily life and morphological appearance. Due to its considerable effect on the quality of life, this disease can lead to depression. However, not many studies have been performed on the quality of life and depression in...

OBJECTIVES The Prediciting factors for response to treatment in carpal tunnel syndrome (PALMS) study is designed to identify prognostic factors for outcome from corticosteroid injection and surgical decompression for carpal tunnel syndrome (CTS) and predictors of cost over 2 years. The aim of this paper is to explore the cross-sectional association of baseline patient-reported and clinical seve...

BACKGROUND Depression is an independent risk factor for coronary artery disease. Autonomic instability may play a mediating or moderating role in this relationship; however this is not well understood. The objective of this study was to explore cardiac autonomic function and cardiac arrhythmia in depression, the correlation between depression severity and Heart Rate Variability (HRV) related in...

s | 13 Abstract Objective: The aim of this post-hoc analysis was to evaluate the effect of depression severity on clinical response in patients with bipolar depression treated with lurasidone. Methods: Patients with bipolar I depression in 2 registration trials were randomized to 6 weeks of once-daily, double-blind, placebo-controlled treatment with lurasidone monotherapy (20–60 mg/d or 80–120...

background: obstructive sleep apnea syndrome (osas) is a common sleep disorder characterized by repeated upper airway obstruction during sleep. while respiratory pauses followed by loud snoring and daytime sleepiness are the main symptoms of osas,the patients may complain from sleep disruption, headache, mood disturbance, irritability, and memory impairment. however, the association of sleep ap...

BACKGROUND Disease severity, illness perceptions, coping strategies, stress, psychological well-being, and quality of life were reported to have close relationships. According to the Common Sense Model, illness perceptions and coping strategies could mediate the relationship between illness stimuli and illness outcomes such as psychological health and quality of life. Stress was also associated...