Previous work (Pearson, 1950; Pearson et al., 1952; and Visser et al., 1952) showed that various compounds may inhibit Theiler's GDVII strain of mouse encephalomyelitis virs in vitro; none tested so far was effective in vivo. It was of interest to determine if compounds capable of depressing centrl nervous stem activity would also repress virl activity. The present report gives the results of t...

The anti-depressant fluoxetine is widely present in the aquatic environment. Typical river concentrations are in the low ng/L range. Many ecotoxicity studies have assessed the effects of this pharmaceutical on a range of aquatic species. Some studies report that ng, or even pg, per litre concentrations cause effects, whereas other studies report that effects only occur when the water concentrat...

The ethanol extract of Coccos nucifera (EECN) was tested for possible pharmacological effects on experimental animals. EECN significantly potentiated the sleeping time of mice induced by standard hypnotics viz. pentobarbital sodium, diazepam, and meprobamate in a dose dependent manner. EECN showed significant analgesic properties as evidenced by the significant reduction in the number of writhe...

The depletion of ore deposits, the increasing demand for raw materials, need to process low-grade, complex and finely disseminated ores, reprocessing tailings are challenges especially froth flotation separation technologies. Even though they capable handling relatively fine grain sizes, very ultrafine particles faces many problems still. Further, low-contrast semi-soluble salt-type minerals wi...

Purpose: The study aimed to assess the depressant or antidepressant effects of several Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in mice: the selective cyclooxygenase-2 (COX-2) inhibitor meloxicam, and the non-selective COX-1 and COX-2 inhibitors lornoxicam, sodium metamizole, and ketorolac. The current literature data regarding such effects of these agents are scarce. Materials and methods...