cystic fibrosis (cf) is a life-limiting autosomal recessive disorder affecting principally respiratory and digestive system . it is caused by cystic fibrosis transmembrane conductance regulator (cftr) gene mutation. the aim of this study was to determine the extent of repeat numbers and the degree of heterozygosity for c.3499+200ta(7_56) and d7s523 located in intron 17b and 1 cm proximal to the...

abstract background iron overload is the main transfusion related side effects in patients with transfusion dependent hemoglobinopathies. severe iron deposition in tissues leads to organ dysfunction. many organs can be affected such as heart, liver, and endocrine organs. cardiac failure and liver fibrosis are the consequent of iron overload in transfusion dependent hemoglobinopathy. magnetic re...

the present study was designed to develop a preliminatory cognitive screeting test battery for differentiating brain damaged patients, from psychiatric patients and normal subjects.based on previous researches, the items scales, administraion and scoring instructions for the test battery were prepared. the test included the following scales: attention, memory, construction ability, receptive la...

The degree of fasting hyperglycemia in patients with non-insulin-dependent diabetes mellitus is dependent on the rate of hepatic glucose production. The basal rate of hepatic glucose production is increased in patients with non-insulin-dependent diabetes mellitus, and there is a positive correlation between hepatic glucose production and fasting glucose levels. Diminished secretion of insulin, ...

BACKGROUND: Total lung capacity (TLC), forced expiratory flow between 25 and 75% (FEF25-75%), peak (PEF), or post-bronchodilator volume response is recommended to detect obstructive abnormalities in the lung. The present study was performed evaluate usefulness of these pulmonary function test (PFT) parameters diagnose disease subjects with a restrictive pattern spirometry. <...