INTRODUCTION Dental pulp has neural fibers that produce neuropeptides like Substance P (SP) and calcitonin gene-related peptide (CGRP). The inflammation of dental pulp can lead to an increase amount of SP and CGRP release, especially in symptomatic irreversible pulpitis. Therefore, it can be assumed that neuropeptides have some role in the progression of inflammation of the dental pulp. The aim...

Objective: To evaluate dental age assessment reliability through Tooth Coronal Index (TCI) method. Material and Methods: The cone-beam computed tomography (CBCT) scans of 160 individuals aged between 20-70 years were analyzed in the present study. height crown, i.e., coronal height, pulp cavity, cavity mandibular second premolars first molars calculated then TCI was measured. actual a subject c...

Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in the dental pulp. These events can lead to pulp healing if the infection is not too severe following the removal of diseased enamel and dentin tissues and clinical restoration of the tooth. However, chronic inflamm...

INTRODUCTION Microarray is a recently developed simultaneous analysis of expression patterns of thousand of genes. The aim of this research was to evaluate the expression profile of human healthy dental pulp in order to find the presence of genes activated and encoding for proteins involved in the physiological process of human dental pulp. We report data obtained by analyzing expression profil...

introduction: open-apex teeth with irreversible pulpitis require complex and difficult treatment. providing the right environment for apexogenesis and pulp protection is vital for their long term prognosis. the young pulp of open apex tooth, however, is better equipped against irritation and assault. the aim of this study was to evaluate pulp inflammation in open apex canine teeth of cats. mate...

to report the association of pulp calcification with that of cardiovascular disease (cvd) using digital panoramic dental radiographs.digital panoramic radiographs of patients referred from the angiography department were included if the patient was under 55 years old and had non-restored or minimally restored molars and canines. an oral and maxillofacial radiologist evaluated the images for pul...

introduction: ca(oh) 2 -containing/forming materials are conventionally used for indirect pulp-capping and are theoretically able to release ca 2+ and oh - ions for hydrolytic dissociation. however, no evidence exists for ion diffusion through the remaining coronal dentin. the aim of this study was to design an innovative experimental set-up to test the ability of ca(oh) 2 -containing and ca(oh...

background: managing dental caries in young children is demanding due to the elusions present on the right diagnostic criteria for treatment. the present study evaluated the histological status of pulp tissues extracted from primary second molar with caries involvement. histological findings are correlated with clinical and radiographic assessment. materials and methods: simple experimental stu...

background: stem cells from human exfoliated deciduous teeth (shed) have the capability to differentiate into neural cells. neurotrophins including nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and neurotrophin-4 (nt-4) have neurogenesis, neurotrophic, or neuroprotective effects and are expressed in developing teeth. the aim of this study was to mea...