introduction: landslides are amongst the most damaging geologic hazards in the world. they pose a threat to the safety of humankind lives as well as the environment, resources and property. compared with other natural hazards such as volcanic eruptions and floods, landslides cause considerable damage to human beings and massive economic losses (guzzetti, 2005). according to preliminary estimates...

Preschoolers often switch a response on repeated questioning, even though no new evidence has been provided (Krahenbuhl, Blades, & Eiser, 2009). Though apparently irrational, this behavior may be understood as children making an inductive inferrence based on their beliefs about whether intial responses were correct and the knowledgeability of the questioner. We present a probabilistic model of ...

The objective of this review is to address the mechanisms of methylmercury (MeHg)-induced neuronal toxicity. Astrocytes play a key role in MeHginduced excitotoxicity as manifested in the following terms: [1] MeHg preferentially accumulates in astrocytes. [2] MeHg potently and specifically inhibits glutamate uptake in astrocytes. [3] Neuronal dysfunction is secondary to disturbances in astrocyte...

s: Pharmaco-MEG and beta frequency neocortical oscillations Ian M. Stanford, School of Life and Health Sciences, Aston University, Birmingham UK Using pharmaco-magnetoencephalography (Hall et al., 2009) we have shown that specific cognitive and motor deficits relate to abnormally elevated slow-wave oscillatory activity in stroke and exaggerated beta frequency activity in Parkinson’s disease (PD...

Cytochromes P450 (P450s) are involved in the oxidative metabolism of a plethora of structurally unrelated compounds, including therapeutic drugs. Two orphan members of the nuclear receptor superfamily, the pregnane X receptor (PXR; NR1I2) and constitutive androstane receptor (CAR; NR1I3) have been implicated in this phenomenon. In the present study, we examined the transcriptional regulation of...

This Special Issue of Geo-Marine Letters compiles papers on marine, estuarine and freshwater mollusc shells as recorders of environmental and climatic conditions. Considering that many past studies have differentiated geochemical investigations from sclerochronological investigations, we propose that the sub-discipline term “sclerochemistry” be used when geochemical investigations are undertake...

Egr-3 is an immediate-early primary response gene encoding a zinc finger transcription factor. We cloned the human Egr-3 genomic locus including greater than 1100 bp of the 5' flanking region and analyzed this region for putative cis-acting elements. The GC-rich promoter forms part of a representative CpG island that extends into the genomic locus. The Egr-3 promoter contains a region of TATA h...

The ability of multidrug-efflux transporters to recognize scores of dissimilar organic compounds has always been considered paradoxical because of its apparent contradiction to some of the basic dogmas of biochemistry. In order to understand, at least in principle, how a protein can recognize multiple compounds, we analysed the transcriptional regulator of the Bacillus subtilis multidrug transp...

I am deeply honoured and delighted to write this statement as the new Editor-in-Chief of Asian Journal Social Psychology. always feel a strong sense connection journal. My history with it began in 2004 when published very first research article my career, which was piece about social perception biases during SARS outbreak, April issue. Three years later, managed publish M.Phil. dissertation stu...

Alternative Text (AltText) is widely recognized as a key principle of digital accessibility and accessible publishing (PAAG, 2023). It has also been discussed creative writing practice (Finnegan & Coklyat, n.d.), an access tool for museums cultural institutions (Wilson, 2011). In the January 2023 issue Curator: The Museum Journal (Cecilia et al., 2023), we considered rather fragmented decadal d...