BACKGROUND The World Health Organization estimates that the global number of dengue infections range between 80-100 million per year, with some studies estimating approximately three times higher numbers. Furthermore, the geographic range of dengue virus transmission is extending with the disease now occurring more frequently in areas such as southern Europe. Ae. aegypti, one of the most promin...

UNLABELLED BACKGROUND Culex is an important mosquito as vectors for the transmission of serious diseases, such as filariasis, West Nile virus, dengue, yellow fever, chikungunya and other encephalitides. Nearly one billion people in the developing countries are at risk. In order to discover new bioactive molecules and pesticides acting on mosquito, we designed active amide structure and synth...

We argue that using more natural blood feeding methods to study mosquito vector competence for dengue viruses and exploring the effect of viral infection on other mosquito life-history traits that influence vectorial capacity will significantly advance our understanding of dengue epidemiology.

Aedes aegypti and Ae. albopictus mosquitoes, primary vectors of dengue and chikungunya viruses, were recently detected in California, USA. The threat of potential local transmission of these viruses increases as more infected travelers arrive from affected areas. Public health response has included enhanced human and mosquito surveillance, education, and intensive mosquito control.

Dengue may be the most widespread arboviral illness worldwide. Most patients with dengue infection have only mild disease or classic dengue fever, with influenza-like symptoms, severe headache, and aching joints and muscles. However, in a small percentage of patients — maybe half a million people every year — potentially lethal forms of dengue called dengue hemorrhagic fever and dengue shock sy...

Two hypotheses for how conditions for larval mosquitoes affect vectorial capacity make opposite predictions about the relationship of adult size and frequency of infection with vector-borne pathogens. Competition among larvae produces small adult females. The competition-susceptibility hypothesis postulates that small females are more susceptible to infection and predicts frequency of infection...

Determinant factors of dengue global epidemiology trends include, but are not limited to: 1) demographic changes including population growth, economical trends in tropical countries and land use patterns; 2) increased urban population size and density due to rural to urban migration 3) modern transportation with increased movement of people, commodities, animals, vectors and pathogens; and 4) c...

tions, 3) low levels of platelets (<100 × 109/L) and 4) increased capillary permeability (5). Our patient fulfi lled all 4 criteria. Few cases of reported DHF fulfi ll criterion 3 due to the short duration of severe thrombocytopenia in mild clinical forms (8). Increased vascular permeability was shown in our patient by the peritoneal and bilateral pleural effusions. The probability of diagnosin...

BACKGROUND Despite dengue dynamics being driven by complex interactions between human hosts, mosquito vectors and viruses that are influenced by climate factors, an operational model that will enable health authorities to anticipate the outbreak risk in a dengue non-endemic area has not been developed. The objectives of this study were to evaluate the temporal relationship between meteorologica...