Plasma leakage is a major pathogenic mechanism of severe dengue, but the etiology remains unclear. The association between endothelial glycocalyx integrity and vascular permeability in older adults with dengue has not been evaluated. A prospective cohort study of adults with undifferentiated fever screened for dengue by RT-PCR or NS1 antigen testing was performed. Patients were assessed daily w...

Dengue is currently the most important arboviral disease in the world, particularly in tropical countries in which the environmental conditions favor the development and proliferation of the mosquito vector. Dengue hemorrhagic fever presents in two phases: an initial phase, which is characterized by sudden onset of fever and a variety of nonspecific signs and symptoms, and a critical phase, whi...

Dengue fever has variable clinical spectrum ranging from asymptomatic infection to life-threatening dengue haemorrhagic fever and dengue shock syndrome. Fever, arthralgia, headache, petechial spots, rash and haemorrhagic manifestations are common features. However, neurologic complications in general are unusual. In this documentation we present a case of dengue encephalitis, which is an uncomm...

BACKGROUND & OBJECTIVES Dengue fever (DF) is associated with significant morbidity and mortality in the tropical and sub-tropical regions of the world. Since there are no effective antiviral drugs for treatment, clinicians often rely on the accurate diagnosis of dengue fever to begin supportive therapy at early stages of the illness. The objective of this study was to develop an in-house dengue...

Dengue virus infection causes dengue fever, Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Thrombocytopenia is common in dengue fever and is always found in DHF/DSS. The pathogenesis of thrombocytopenia is poorly understood. To further understand the relationship between anti-dengue virus antibody and anti-platelet antibody, we generated monoclonal anti-dengue virus antibodies ...

INTRODUCTION We conducted this study to determine the frequency of malaria and dengue-malaria co-infection in patients admitted to our hospital as 'probable' cases of dengue fever during the 2012 outbreak of dengue, and to ascertain whether dengue-malaria co-infection was more severe than either infection alone. METHODS This cross-sectional observational study was conducted at Jinnah Hospital...

Dengue fever (DF) is amosquitoborne disease spread by female Aedes mosquito. transmission depends on the changing of climatic parame- ters like temperature, humidity, rainfall, as well congestion in an area, i.e., where population density high. In this review, we have highlighted reasons occurrence DF and methods for early detection same. Symptoms are key points to diagnose dengue patients. Man...

Dengue fever is a common viral illness seen worldwide with higher incidence in tropical regions. The may present as mild nonspecific symptoms to life-threatening severe dengue. Severe dengue usually secondary infection which uncommon during infancy. As the virus classically not known be neurotropic virus, neurological manifestations are atypical presentations of child fever, seizures, altered m...


 There are 5 dengue cases in 19 neighborhoods with 1 death rate 2022. This study aims to determine the application of DBD vector control management Environment Belawan Bahagia Village.This is a qualitative research using Descriptive Analytics method, 3 informants criteria that have been set by researcher. The result this there no program yet causes Dengue Hemorrhagic Fever (DHF) biologica...

Background: Dengue viral infection is common worldwide caused by dengue virus. Recent studies have shown dengue viral infection causing encephalitis with high morbidity and mortality. The Dengue encephalitis patients usually present with altered sensorium, elevated lab parameters and high antibody titres at the time of admission. Aims: To compare initial lab parameters, clinical spectrum and ou...