Moderate acoustic overexposure in adult rodents is known to cause acute loss of synapses on sensory inner hair cells (IHCs) and delayed degeneration of the auditory nerve, despite the completely reversible temporary threshold shift (TTS) and morphologically intact hair cells. Our objective was to determine whether a cochlear synaptopathy followed by neuropathy occurs after noise exposure in pub...

BACKGROUND Patients with chronic pain frequently suffer affective disorders, particularly anxiety and depression. Although clinical research on the relationship between pain and depressive symptoms has been done, it is not clear whether pain causes depression or depression exaggerates pain. To investigate the relation between pain and affect, we measured anxiety and depression-related behaviors...

I ntroduction: Multifocal motor neuropathy (MMN) is a rare, treatable, immune-mediated neuropathy often associated with multifocal conduction block (CB). The hallmark electrodiagnostic feature is the presence of CB occurring at non-entrapment sites. However, MMN without CB has also been described and can be diagnosed, even in the absence of CB. Therefore, it is crucial to diagnose and identify ...

conclusions both tens and prf lumbar sympathectomy are promising pain relief treatments for painful dnp. however, prf lumbar sympathectomy seems to have a superior efficacy. further studies with a larger sample size and a longer follow-up period are needed. background painful diabetic peripheral neuropathy (dpn) is a long-term complication of type 1 and type 2 diabetes that majorly impacts qual...

background: diabetes mellitus (dm) is a common non-communicable diseases associated with different complications. the study aim was to analyze and report characteristics of research output in the field of diabetes complication in iran in details and identify research gap in this field. methods: all scientific diabetes output published by iranian authors in national and international journals un...

toxic optic neuropathy (ton) is a group of medical disorders which can be defined by visual impairment due to optic nerve damage by a toxin. the exposure to a toxic substance can occur at the workplace, with ingestion of materials/ foods containing a toxin, or the use of systemic medications. ton is a disease entity which is not only under-diagnosed, but also often diagnosed at a stage when rec...

Acute limb compartment syndrome (ALCS) is defined as compound symptoms resulting from poor oxygenation and decreased nutrition supply to muscles and nerves in a tightly confined compartment. The most common cause of ALCS is tibia fracture, followed by blunt trauma to soft tissue. However, non-traumatic causes are rare. We report an iatrogenic, non-traumatic ALCS case after venoarterial extracor...

Inflammatory neuropathies may be due to infection (with a specific casual agent identified) including Lyme disease, HIV, Leprosy, Herpes Zoster, Hepatitis B & C. The other group of are Autoimmune or possibly infectious (but with no specific causal infectious agent identified) including sarcoidosis, Guillain-Barre syndrome/ acute inflammatory demyelinating polyneuropathy ( AIDP), chronic in...

Although clinical, pathological, and biochemical effects of organophosphorus-induced delayed neuropathy (OPIDN) have been intensively investigated in the adult hen, detailed electrophysiological studies are lacking. Adult white leghorn hens were treated with a single oral dose of either 30 mg/kg tri-2-cresyl phosphate (TOCP), 750 mg/kg TOCP, 4 mg/kg di-n-butyl-2,2-dichlorovinyl phosphate (DBCV)...

A distal symmetrical sensory peripheral neuropathy is frequently observed in people living with Human Immunodeficiency Virus Type 1 (HIV-1). This neuropathy can be associated with viral infection alone, probably involving a role for the envelope glycoprotein gp120; or a drug-induced toxic neuropathy associated with the use of nucleoside analogue reverse transcriptase inhibitors as a component o...