We report a case of fatal pulmonary disease in a patient infected with human immunodeficiency virus (HIV), where cytomegalovirus (CMV) was the only causative agent identified in the lungs at autopsy. The most prominent histopathological features were numerous interalveolar cells containing CMV inclusion bodies combined with scanty signs of inflammation. We propose that the lung damage caused by...

cd27 is a biomarker associated with both t-cells and b-cells activation .plasma soluble cd27 (scd27) was identified as  a marker of disease outcome in human immunodeficiency virus (hiv) infection .testing of plasma scd27 represents a good tool to monitor the change of immune activation during hiv infection.we sought to analyses role of hepatitis c virus (hcv) and also gb virus type c (gbv-c) co...

Heme oxygenase-1 (HO-1) is a highly inducible and ubiquitous cellular enzyme that subserves cytoprotective responses to toxic insults, including inflammation and oxidative stress. In neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and multiple sclerosis, HO-1 expression is increased, presumably reflecting an endogenous neuroprotective response against ongoing cellula...

Submit Manuscript | http://medcraveonline.com Abbreviations: AIDS: Acquired Immune Deficiency Syndrome; AR: Attack Rate; ARI: Acute Respiratory Infections; aOR: Adjust Odd Ratio; CFP: Case Fatality Proportion; CFR: Case Fatality Rate; CI: Confidence Interval; DNA: Deoxyribonucleic Acid; HAART: Highly Active Antiretroviral Therapy; HIV: Human Immunodeficiency Virus; ILI: Influenza-Like Illness; ...

BACKGROUND Hepatitis B and C viral co-infections with human immunodeficiency virus (HIV) are known to affect progression, management, and outcome of HIV infection. This study was aimed to access the prevalence of hepatitis B and C co-infections in HIV-infected adult patients in the University of Benin Teaching Hospital with a view of understanding the gravity of this problem in the local popula...

background: human immunodeficiency virus (hiv) makes infected cases prone to opportunistic infections like tuberculosis (tb) due to impaired immunity of the body, especially multi drug resistant (mdr) ones which are a major concern. with hiv outbreak starting late in the 20th century, the international health community is observing a huge rise in the incidence of this complex disease. herein, w...

background & objective: interleukin (il)-10 is an important anti-inflammatory and immunomodulatory cytokine. some authors believe that single nucleotide polymorphisms (snp) in the promoter region of the il-10 gene have been associated with susceptibility to hiv infection and progression to aids, but its role is not clearly defined yet. the present study was undertaken to evaluate the associ...

background & aim: acquired immune deficiency syndrome (aids) is an infectious disease caused by human immunodeficiency virus (hiv). the awareness of hiv preventive measures and its transmission routes have an important role in controlling the hiv infection in the society. regarding this, the present study aimed to investigate the awareness and attitudes of the high school students regarding hiv...

Retroviral Gag polyproteins are necessary and sufficient for virus budding. Productive HIV-1 Gag assembly takes place at the plasma membrane. However, little is known about the mechanisms by which thousands of Gag molecules are targeted to the plasma membrane. Using a bimolecular fluorescence complementation (BiFC) assay, we recently reported that the cellular sites and efficiency of HIV-1 Gag ...