c-Met, a type of receptor tyrosine kinase, may be significantly associated with the progression of hepatocellular carcinoma (HCC). In addition, des-γ-carboxyprothrombin (DCP) has been found to interact with c-Met and activate HCC cell growth. Therefore, the functional inhibition of c-Met expressed on HCC cells should arrest HCC cell growth. The present study found that the c-Met inhibitor SU112...

A simple and reliable method using on-line purge and trap gas chromatography mass spectrometry has been developed for the determination of the fumigant 1,3-dichloropropene (1,3-DCP) in agricultural water and soil samples. The proposed analytical methodology was validated in the target environmental matrices by the analysis of spiked blank matrix samples. Limit of detection values of 0.05 microg...

Activated carbon prepared from coir pith (ZnCPC) using ZnCl2 was investigated to find the feasibility of its application for removal of 2,4–dichlorophenol (2,4-DCP) in aqueous solution through adsorption process. Batch mode kinetics and isotherm studies were carried out to evaluate the effects of contact time, initial concentration, adsorbent dose, pH, and temperature. Lagergren, Second order, ...

Distributed collaboration problem (DCP) is a kind of distributed resource allocation problem. Previous works give the solution of DCP with non-conflictive tasks. In this paper, we present a completely distributed algorithm (CDA) to solve DCP with conflictive tasks where each task requires exactly two resources. We call this the measurement collaboration problem (MCP). We prove the aliveness and...

The 2 main degradative pathways that contribute to proteostasis are the ubiquitin-proteasome system and autophagy but how they are molecularly coordinated is not well understood. Here, we demonstrate an essential role for an effector caspase in the activation of compensatory autophagy when proteasomal activity is compromised. Functional loss of Hsp83, the Drosophila ortholog of human HSP90 (hea...

EUS-guided direct cholangio-pancreatic access (EUS-DCP) may be feasible in patients with an inaccessible papilla [1], however, it poses a challenge due to its technical difficulty and relatively high complication rate [2,3]. EUS-rendezvous may be a more feasible alternative for antegrade cholangiopancreatography (EUS-RV) in patients with an inaccessible papilla than EUS-DCP. Even in expert hand...

A 45-year-old man was admitted to our hospital because of chronic hepatitis C and a large liver tumor accompanied by increased serum levels of alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP), the tumor markers for hepatocellular carcinoma. Endoscopic examination revealed advanced gastric cancer. Biopsy specimens of the stomach and liver showed gastric adenocarcinoma and its meta...

Alcaligenes eutrophus JMP222, a derivative of A. eutrophus JMP134 which has lost plasmid pJP4 (encoding the tfd genes for the ortho fission pathway), was induced for the meta fission pathway when grown on o-cresol. Resting cell suspensions, grown on o-cresol, oxidized 2,4-dichlorophenol (2,4-DCP), a degradation product of 2,4-dichlorophenoxyacetic acid, to 3,5-dichlorocatechol. Further degradat...

OBJECTIVE To measure the ultrasound propagation velocity (UV) through a tibial transverse osteotomy in sheep, before and after the fixation with a DCP plate. MATERIAL AND METHODS Ten assemblies of a DCP plate with the diaphyseal segment of tibiae, in which a transverse osteotomy was made, were used. Both coronal and sagittal transverse and the axial UV were measured, first with the intact bon...

Amblyomma cajennense (Acari: Ixodidae) é um carrapato de grande importância sócioeconômica no subcontinente Sul-Americano. Apesar disso, pouco se conhece acerca de sua ecologia química, cuja informação é crucial para o seu controle. Nesse estudo, 2,6-diclorofenol (2,6-DCP), o feromônio sexual de A. cajennense foi quantificado por cromatografia gasosa acoplada a espectrometria de massas no modo ...