objective(s)marfan syndrome (mfs) is a severe connective tissue disorder withan autosomal dominant inheritance pattern. early diagnosis is critical in mfs. because of the large size of fibrillin-1 gene (fbn1), the uniqueness of mutations, and the absence of genotype-to-phenotype correlations linkage analysis can be very helpful for early diagnosis of mfs. in this study, eight polymorphic marker...

background: hearing loss (hl) is the most frequent neurosensory impairment. hl is highly heterogeneous defect. this disorder affects 1 out of 500 newborns. this study aimed to determine the role of dfnb2 locus and frequency of myo7a gene mutations in a population from west of iran. methods: thirty families investigated in shahrekord university of medical sciences in 2014, genetic linkage analys...

objective: this article presents an application of cluster analysis for social sciences researches especially those studies that have an interview as part of their data collection. this application is more suitable for sequential mixed method researchers who use quantitative data to frame subsequent qualitative subsamples for conducting interviews.  methods: in more detail, the algorithm (i.e.,...

Record linkage clusters records such that each cluster corresponds to a single distinct real-world entity. It is a crucial step in data cleaning and data integration. In the big data era, the velocity of data updates is often high, quickly making previous linkage results obsolete. This paper presents an end-to-end framework that can incrementally and efficiently update linkage results when data...

In current world, the immense size of a data set makes problems in finding similar/identitcal data. In addition, the dirtiness of data, i.e. typos, missing/tilting information, and additional noises usually occurred by careless editing or entry mistakes, makes further difficulty to identify entity-belongs. Therefore, we focus on the faster detection of data referring the same real-world entity ...

INTRODUCTION In order to identify priorities for building integrated surveillance systems that effectively model and predict human risk of zoonotic diseases, there is a need for improved understanding of the practical options for linking surveillance data of animals and humans. We conducted an analysis of the literature and characterized the linkage between animal and human health data. We disc...

Objective: This article presents an application of cluster analysis for social sciences researches especially those studies that have an interview as part of their data collection. This application is more suitable for sequential mixed method researchers who use quantitative data to frame subsequent qualitative subsamples for conducting interviews.  Methods: In more detail, the algorithm (i....

Missing genotype data can increase false-positive evidence for linkage when either parametric or nonparametric analysis is carried out ignoring intermarker linkage disequilibrium (LD). Previously it was demonstrated by Huang et al. [1] that no bias occurs in this situation for affected sib-pairs with unrelated parents when either both parents are genotyped or genotype data is available for two ...

OBJECTIVE To review the literature on the views of healthcare professionals to the linkage of healthcare data and to identify any potential barriers and/or facilitators to participation in a data linkage system. METHODS Published papers describing the views of healthcare professionals (HCPs) to data sharing and linkage were identified by searches of Medline, EMBASE, SCOPUS, CINAHL, and PsychI...

the nitrite ® nitro isomerization in nitritopentaamine cobalt (iii) halides has been known. in this paper, the effect of the size of the counter ions (noncoordinated groups) on the rate of isomerization in nitritopentaamine cobalt (iii) halides, is reported. the rate of isomerization is decreased by increasing the size of the counter ions. this decrease is explained on the basis of steric inter...