DNA damage repair is an essential cellular mechanism that maintains genome stability. Here, we show that the nonmethylable cytidine analog zebularine induces a DNA damage response in Arabidopsis thaliana, independent of changes in DNA methylation. In contrast to genotoxic agents that induce damage in a cell cycle stage-independent manner, zebularine induces damage specifically during strand syn...

conclusions the findings suggest that estrogen supplementation increases damage in testicular tissue due to eccentric exercise. results conventional light microscopic results revealed that testes tissues of the eccentric exercise administered group and the estrogen supplemented group exhibited slight impairment. in groups that were both eccentrically exercised and estrogen supplemented, more de...

in this paper, a crack localization method for euler-bernoulli beams via an efficient static data based indicator is proposed. the crack in beams is simulated here using a triangular variation in the stiffness. static responses of a beam are obtained by the finite element modeling. in order to reduce the computational cost of damage detection method, the beam deflection is fitted through a poly...

results of damage prediction in buildings can be used as a useful tool for managing and decreasing seismic risk of earthquakes. in this study, damage spectrum and c4.5 decision tree algorithm were utilized for damage prediction in steel buildings during earthquakes. in order to prepare the damage spectrum, steel buildings were modeled as a single-degree-of-freedom (sdof) system and time-history...