To evaluate the effects of ambroxol hydrochloride on lung tissue cell apoptosis and vascular remodeling in rats with smoke induced chronic obstructive pulmonary disease. Sprague Dawley were randomly divided into normal, model, experimental control groups (n=20). The rat model disease was established by fumigation using Yan’an Cigarettes for 64 d. After fumigation, subcutaneously injected 5 mL A...

Purpose: high tibial osteotomy (HTO) is a recommended treatment for medial compartment knee osteoarthritis. Newer cartilage regenerative procedures may add benefits to the result of HTO. In this prospective study we investigate safety and also results of HTO associated with bone marrow derived cells (BMDC) transplantation in relatively young and middle aged active individuals with early osteoar...

  Background : Biomechanical factors are known to be important in knee osteoarthritis (OA) development and progression. This study was designed to determine changes of hamstrings muscle activation, knee adduction moment and ankle rotation angle in two knee osteoarthritis (mild and moderate) and a healthy control group.   Methods: 16 females (10 with mild and 6 with moderate medial knee osteoart...

Background: Acquiring knowledge about anatomic and geometric quantities of bones is among the most vitalparameters in orthopedic surgery that has a significant effect on the treatment of various disorders and subsequentoutcomes. The aim of this study was to obtain anthropometric information for distal femur in order to compare withsimilar dimensions of prosthesis used in total...

The amidation of a synthetic peptide D-Tyr-Pro-Gly-Gly by sheep hypothalamic and pituitary preparations was measured. This substrate was designed as a glycine-extended C-terminal peptide analogue of gonadotropin-releasing hormone (GnRH) to test the ability of these tissues to convert the product produced by cleavage of the GnRH prohormone into the active amidated decapeptide. An alpha-amidating...