This investigation was aimed to compare the inference of antelope phylogenies resulting from the 16S rRNA, cytochrome-b (cyt-b) and d-loop segments of mitochondrial DNA using three different computational models including Bayesian (BA), maximum parsimony (MP) and unweighted pair group method with arithmetic mean (UPGMA). The respective nucleotide sequences of three Oryx species (Oryx leucoryx, ...

BACKGROUND Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been described for different types of cancers and might be associated with cancer risk and disease outcome. We used a population-based series of esophageal squamous cell carcinoma (ESCC) patients for investigating the prediction power of SNPs in mitochondrial D-lo...

In order to support analysis of channel catfish populations and genetic improvement programs, the channel catfish, Ictalurus punctatus, mitochondrial genome was completely sequenced and revealed gene structure and gene order common to vertebrates. Nucleotide sequence comparisons of cytochrome b (Cytb) and cytochrome c oxidase subunit 1 (COI) demonstrated genetic separation of the genera Ictalur...

In European countries, hunting of wildlife is regulated by various directives. However, illegal activities are becoming more common. To deal with crime cases, it becomes necessary to select the best molecular markers for analysis animal sex, species, and relationships identification. This study investigated potential within chromosomal mitochondrial DNA (mtDNA) forensics. By applying targeting ...

A simulation-based study of variability remnant polarization $\left (P_r \right)$ in a multi-granular 3-D ultra-thin ferroelectric (FE) capacitor is presented this paper. The Poisson Voronoi Tessellation Diagram (PVD) used for the nucleation grains FE region, which corresponds to physical growth mechanism. PVD algorithm implemented MATLAB coupled with TCAD simulations, trace hysteresis loop. It...

A central paradigm in immunology states that successful generation of high affinity antibodies necessitates an immense primary repertoire of antigen-combining sites. Much of the diversity of this repertoire is provided by varying one antigen binding loop, created by inserting randomly a D (diversity) gene out of a small pool between the V and J genes. It is therefore assumed that any particular...

We study general non-supersymmetric heterotic string models, including so-called interpolating $d$-dimensionally compactified with the arbitrary number of freely acting $\mathbb{Z}_{2}$ twisted directions. Taking limits radii to zero and infinity (the endpoint limits), we show some examples various interpolation patterns in $d=2$ (8-dimensional) case. In region where supersymmetry is asymptotic...

Hepatocyte growth factor (HGF) has a strong affinity for heparin. About one fourth of HGF secreted from MRC-5 human embryonic lung fibroblast cells was found to be associated with heparin and heparan sulfate proteoglycan on the cell surface and extracellular matrix. To identify heparin-binding sites within the HGF molecule, we constructed variously deleted mutant HGFs and examined their binding...

The aim of this work is to develop new approaches for the synthesis of protein epitope mimetics. These should be conformationally well defined molecules, that accurately mimick the stuctures and properties of exposed surface regions of peptides and proteins. Here we describe the synthesis and application of a dipeptide template, comprising L-4-aminoproline (Apro) and D-proline (D-Pro), to induc...

The nucleotide state of actin (ATP, ADP-P(i), or ADP) is known to impact its interactions with other actin molecules upon polymerization as well as with multiple actin binding proteins both in the monomeric and filamentous states of actin. Recently, molecular dynamics simulations predicted that a sequence located at the interface of subdomains 1 and 3 (W-loop; residues 165-172) changes from an ...