We argue that the early universe may be described by an initial state of space-filling branes and anti-branes. At high temperature this system is stable. At low temperature tachyons appear and lead to a phase transition, dynamics, and the creation of D-branes. These branes are cosmologically produced in a generic fashion by the Kibble mechanism. From an entropic point of view, the formation of ...

there is no report on the etiology of acute viral hepatitis in sistan and baluchestan province, southeast of iran. we performed this study to compare the clinical, biochemical and demographic properties of acute viral hepatitis (avh) in this province. demographic and clinical data were collected from 263 patients with avh. they were tested for hbsag, igm anti-hav, igm anti-hbc, igm anti-hdv, or...

Carboplatin-paclitaxel (CP) is standard of care (SOC) for first-line treatment primary A/R EC; median OS <3 yrs. Use anti–PD-1s with chemo has improved outcomes in multiple tumour types. RUBY (NCT03981796) evaluated the efficacy and safety anti–PD-1 dostarlimab (D)+CP EC compared CP alone. a phase III, global, randomised, double-blind, multicentre, PBO-controlled study. Pts advanced stage III o...

We examine the degree to which fluctuating dynamics on exponentially expanding spaces remember initial conditions. In de Sitter space, the global late-time configuration of a free scalar field always contains information about early fluctuations. By contrast, fluctuations near the boundary of Euclidean Anti-de Sitter may or may not remember conditions in the center, with a transition at ∆ = d/2...

BACKGROUND Chemoresistance is a major obstacle to successful chemotherapy for human non-small cell lung cancer (NSCLC). Astragaloside IV, the component of Astragalus membranaceus, has been reported to exhibit anti-inflammation, anti-cancer and immunoregulatory properties. In the present study, we investigated the role of astragaloside IV in the chemoresistance to cisplatin in NSCLC cells. MET...

The (single) black hole solutions of Ba~ nados, Teitelboim and Zanelli (BTZ) in 2+1 dimensional anti-de Sitter space are generalized to an arbitrary number n of such black holes. The resulting multi-black-hole (MBH) spacetime is locally isometric to anti-de Sitter space, and globally it is obtained from the latter as a quotient space by means of suitable identiications. The MBH spacetime has n ...

Bakcground: The aim of ITP treatment is to prevent intracranial hemorrhage and increase the platelet count rapidly. This study was conducted with the objective of comparing the efficacy of anti-D immunoglobulin (Ig) with dexamethasone in treating childhood ITP. Materials and Methods: In this randomized prospective control trial, 20 ITP patients (Platelet count<20,000/&micro;l) younger th...

Blood Transfus 2007; 5: 44 DOI 10.2450/2007.0008-07 © SIMTI Servizi Srl The D antigen of the Rh blood system is the most important red blood cell antigen determined by a protein, because D-negative individuals are easily anti-D immunised. Individuals, whose cells have a qualitative variation of the D antigen (partial D) lacking one or more components of the D antigen, are said to have a partial...