نتایج جستجو برای: cytotoxic therapy

تعداد نتایج: 702526  

Journal: :The Journal of Experimental Medicine 2004
Catherine M. Bollard Laura Aguilar Karin C. Straathof Benedikt Gahn M. Helen Huls Alexandra Rousseau John Sixbey M. Victoria Gresik George Carrum Melissa Hudson Dagmar Dilloo Adrian Gee Malcolm K. Brenner Cliona M. Rooney Helen E. Heslop

Epstein Barr virus (EBV)+ Hodgkin's disease (HD) expresses clearly identified tumor antigens derived from the virus and could, in principle, be a target for adoptive immunotherapy with viral antigen-specific T cells. However, like most tumor-associated antigens in immunocompetent hosts, these potential targets are only weakly immunogenic, consisting primarily of the latent membrane protein (LMP...

2017
Qin Tang Jianyu Cui Zhonghua Tian Jiangchuan Sun Zhigang Wang Shufang Chang Shenyin Zhu

BACKGROUND Photodynamic therapy and sonodynamic therapy are developing, minimally invasive, and site-specific modalities for cancer therapy. A combined strategy PSDT (photodynamic therapy followed by sonodynamic therapy) has been proposed in this study. Here, we aimed to develop novel biodegradable poly(DL-lactide-co-glycolic acid) phase-transition nanoparticles simultaneously loaded with oxyge...

Journal: :Advanced Functional Materials 2021

Immunotherapy is an efficient approach to clinical oncology. However, the immune privilege of central nervous system (CNS) limits application immunotherapeutic strategies for brain cancers, especially glioblastoma (GBM). Tumor resistance checkpoint inhibitors a further challenge in immunotherapies. To overcome immunological tolerance tumors, novel multifunctional nanoparticle (NP) highly synerg...

Journal: :The European respiratory journal 1999
J C Grutters L Brinkman M M Aslander J M van den Bosch L Koenderman J W Lammers

Eosinophils play an important role in the pathogenesis of asthma. Several pro-inflammatory responses of eosinophils are primed in vivo in this disease. The aim of the present study was to investigate whether regular antiasthma treatment could modulate priming-sensitive cytotoxic mechanisms of human eosinophils. In a randomized, two-centre, double-blind parallel group study, the effect of 8 week...

Journal: :research journal of pharmacognosy 2014
s. esmaeili m. hamzeloo-moghadam s. ghaffari m. mosaddegh

background and objectives: cancer is a public health problem all over the world. herbal medicines have a vital role in the prevention and treatment of cancer and large numbers of plants and their isolated constituents have shown potential anticancer activity. methods: twenty seven medicinal plants from southern iran provinces have been extracted with methanol and screened for their cytotoxic ac...

Journal: :Frontiers in Medicine 2023

Hemophagocytic lymphohistiocytosis (HLH) is a rare histiocytic disorder characterized by reactive hyperplasia of the mononuclear phagocytic system, which primarily caused dysfunction cytotoxic killer cells and natural cells, leading to antigen clearance barriers overactivation system due continuous stimulation. HLH encompasses group clinical syndromes marked overproduction inflammatory cytokine...

Journal: :Indian Journal of Pharmaceutical Sciences 2022

To study and analyze the effect of bevacizumab-related hypertension on prognosis patients with colorectal cancer non-small cell lung cancer. The randomly selected 100 who received therapy in our hospital from October 2019 to 2021. Among them, adopted intervention for bevacizumab combined cytotoxic drug chemotherapy standard chemotherapy. Bevacizumab treatment has better therapeutic than patient...

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