نتایج جستجو برای: cytogenetics
تعداد نتایج: 10190 فیلتر نتایج به سال:
The goldenberry, Physalis peruviana L., is an important fruit in Colombia due to its export value and nutritional quality. However, commercial crops face challenges of heterogeneity the presence diseases that reduce yield These drawbacks could be handled through different breeding methods develop uniform cultivars, for example, anther culture, which used rapidly produce homozygous lines. ploidy...
BYSTANDER EFFECTS DUE TO NEUTRONS, AND LOW-DOSE HYPER-RADIOSENSITIVITY TO GAMMA RAYS IN HUMAN CELLS USING CYTOGENETICSby
Cytogeneticists recognize that karyotypic abnormalities are associated with specific malignancies. In 1960, Nowell described the Philadelphia chromosome (Ph) and its relationship to chronic myelogenous leukemia (CML). Subsequent work in molecular genetics and biology has revealed that the Ph is a translocation that causes fusion of gene sites that code for the break cluster region (BCR) and the...
ABC Fax + 41 61 306 12 34 E-mail [email protected] www.karger.com © 2003 S. Karger AG, Basel 0301–0171/03/1012–0136$19.50/0 Accessible online at: www.karger.com/cgr Abstract. Contrasting results (random segregation or cosegregation of isomorphic chromosomes) have been reported up to now on the segregation pattern of Robertsonian metacentric chromosomes of Mus musculus domesticus in multiple hete...
ABC Fax + 41 61 306 12 34 E-mail [email protected] www.karger.com © 2004 S. Karger AG, Basel 0301–0171/04/1051–0126$21.00/0 Accessible online at: www.karger.com/cgr Abstract. Nasonia vitripennis is a small parasitic hymenopteran with a 50-year history of genetic work including linkage mapping with mutant and molecular markers. For the first time we are now able to anchor linkage groups to specif...
The MCRN-003/CCTGMYX.1 is a single arm phase II trial of weekly carfilzomib, cyclophosphamide and dexamethasone (wKCd), exploring convenient immunomodulator (IMiD)-free regimen in relapsed myeloma. Weekly carfilzomib (20/70 mg/m2), 40 mg 300 mg/m2 was delivered over 28-day cycles. primary endpoint overall response after four Secondary endpoints included toxicity, depth, PFS OS. Exploratory the ...
INTRODUCTION Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder characterized by progressive accumulation of morphologically and immunophenotypically mature lymphocytes. Characterization of genomic aberrations may help to understand the pathogenesis of CLL and may give prognostic information independent from conventional clinical markers for a risk-adapted management of...
Decades before the recent advances in molecular biology and the knowledge of the complete nucleotide sequence of several genomes, cytogenetic analysis provided the first information concerning the genome organization. Since the beginning of cytogenetics, great effort has been applied for understanding the chromosome evolution in a wide range of taxonomic groups. The exploration of molecular bio...
Clinical animal cytogenetics development began in the 1960's, almost at the same time as human cytogenetics. However, the development of the two disciplines has been very different during the last four decades. Clinical animal cytogenetics reached its 'Golden Age' at the end of the 1980's. The majority of the laboratories, as well as the main screening programs in farm animal species, presented...
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