rosemary (rosmarinus officinalis) is a common household plant grows in many parts of the world, including iran. rosemary leaves are used in folk medicine as an antispasmodic, analgesic, diuretic and ntiepileptic agent. the objective of this study was to investigate the antinociceptive mechanisms of rosemary extract using a writhing test as a model of visceral pain. possible antinociceptive mech...

Dr. Ronaldo Arkader – Department of Pediatric Intensive Care, Hospital Sabará Rua Dona Antonia de Queiros 505 01307-010 São Paulo SP Brasil. E-mail: [email protected] Shapiro syndrome, first described in 1969, is an extremely rare condition consisting of the clinical triad of recurrent hypothermia, sweating, and chills in the presence of agenesis of the corpus callosum. The periodicity of th...

MK-212 (1 x 10(-7)M -- 1 x 10(-5)M) produced dose-dependent contractions of guinea pig ileum, taenia coil and rat fundus strip. The responses to MK-212 in all three preparations were blocked competitively by cyproheptadine (1 x 10(-8)M) a 5-HT receptor antagonist. Mepyramine (1 x 10(-8)M)-H1 receptor antagonist also inhibited competitively the responses of guinea pig ileum and taenia coli to MK...

Objectives: This study determined the chemical composition of essential oil obtained from fresh leaf Plectranthus aegyptiacus, and evaluated it for novelty-induced behavioural (NIB) determine its mechanism(s) action in mice. Methods: The was hydro-distillated, analyzed using gas chromatography-mass spectrometry. effects (50, 100 150 mg/kg; i.p., n=6) on assessed open field test head dipping hol...

BACKGROUND Clinically, elderly patients with unresectable bulky hepatocellular carcinoma (HCC) are difficult to manage, especially in those with co-infections of hepatitis B and C virus. Herein, we reported such a case treated with radiotherapy (RT) by using combined simultaneously integrated inner-escalated boost and volumetric-modulated arc radiotherapy (SIEB-VMAT). After RT, significant symp...

Chlorpromazine 25 mg intramuscular' Cyproheptadine 4 mg every 2-4 hours (0.5 mg/kg/day)8 Propranolol 20 mg three times a day by mouth' Methysergide 2-6 mg/24 hours" Benadryl 50 mg intramuscular'2 Clonazepam 0.5 mg intravenous" (D) The presence of at least three of altered symptoms, and lethal catatonia. There is considerable overlap with neuroleptic malignant syndrome, and many patients may be ...

Pruritus is a major symptom of several dermatological diseases but has limited therapeutic options available. Animal models replicating the pathophysiology of pruritus are needed to support the development of new drugs. Induction of pruritus by chloroquine (CQ) in mice is widely used, although, as with similar models, it has low throughput and does not distinguish between antipruritic effects a...