Arthritis refers to different medical conditions associated with disorder of the primary structures that determine joint functions such as bones, cartilage and synovial membranes. Drug discovery and delivery to retard the degeneration of joint tissues are challenging. Current treatments of different arthritis involves administration of ideal non-steroidal anti-inflammatory drugs (NSAIDs) but ar...

Background: Nutrition is a significant risk factor for the incidence of periodontal disease. Nutrients acting on human genome, either directly or indirectly, can change expression and structure genes. One micronutrients associated with periodontitis vitamin D. Vitamin D has an important role in bone calcium metabolism regulates serum phosphate concentrations at normal limits. Purpose: To discus...

Microspheres are a new category of novel drug delivery system which targets to increase the bioavailability and is formulated expediently obtain prolonged or controlled in body. Aceclofenac; non steroidal anti inflammatory drug, used treat hurting rheumatic conditions such as osteoarthritis, rheumatoid arthritis alkylosing spondylitis. It eases pain reduces inflammation at various sites. Aceclo...

Osteoarthritis is a common, chronic condition which requires an individualised management plan involving multiple kinds of treatment. Exercise programs and the Arthritis Self-Management Program reduce pain and disability associated with osteoarthritis. Paracetamol is the most appropriate first-line analgesic. Non-steroidal anti-inflammatory drugs may be used as second-line analgesia on an as-ne...

1. macroscopically normal human lung tissue was obtained from operative specimens removed for lung cancer and challenged with antigen or calcium ionophore. The release of histamine and slow-reacting substances was measured by fluorimetric and bioassay techniques respectively. 2. Benoxaprofen, a drug with inhibitory effects on the lipoxygenase and cyclo-oxygenase pathways, caused a dose-related ...