نتایج جستجو برای: cvid
تعداد نتایج: 525 فیلتر نتایج به سال:
BACKGROUND Hypogammaglobulinemia may be part of several different immunological or malignant conditions, and its origin is not always obvious. Furthermore, although autoimmune cytopenias are known to be associated with common variable immunodeficiency (CVID) and even may precede signs of immunodeficiency, this is not always recognized. Despite novel insight into the molecular immunology of comm...
CVID is the commonest serious antibody deficiency in adults. There are a number of associated complications including autoimmunity, of which immune thrombocytopenic purpura (ITP) is a relatively common example. ITP usually responds to treatment with corticosteroids, other immunosuppression, splenectomy or high dose intravenous immunologlobulin (IVIG). The management of ITP refractory to these t...
Background The prevalence rate of сommon variable immunodeficiency (CVID), the most common symptomatic form primary disease (PID), is growing every year. In Republican Register PID in Chuvash Republic (Russia) there are 32 patients with CVID, 5 (15.6%) whom have CVID combined an autoimmune - rheumatoid arthritis (RA). immunological studies occupy a large place diagnosis and diseases. Objectives...
Introduction: Common variable immunodeficiency (CVID) is the most common symptomatic in adults. We aimed to reveal mortality rates, causes of CVID patients as well demographic and clinical characteristics differences survived dead patients, effect platelet counts on these patients. Materials methods: The study group included 50 [(Female: 23 (46%), Male: 27 (54%)] with CVID, who were followed-u...
Introduction: Common Variable Immunodeficiency (CVID) is the most prevalent primary immunodeficiency in adult population. The diagnosis based on low concentration of at least 2 immunoglobulin classes, mostly IgG, with IgA and/or IgM. Beside recurrent infections, patients CVID usually suffer from different respiratory, gastrointestinal, autoimmune and malignant diseases. Leading therapeutic appr...
The aim of the present study was to investigate to what extent interstitial lung disease (ILD) in common variable immunodeficiency disorder (CVID)-associated granulomatous disease (GD) is similar to pulmonary sarcoidosis 20 patients with CVID/GD were included in a retrospective study conducted by the Groupe Sarcoïdose Francophone. Medical records were centralised. Patients were compared with 60...
In the present narrative review, we analyzed the relationship between seronegative celiac disease (SNCD) and immunoglobulin deficiencies. For this purpose, we conducted a literature search on the main medical databases. SNCD poses a diagnostic dilemma. Villous blunting, intraepithelial lymphocytes (IELs) count and gluten "challenge" are the most reliable markers. Immunohistochemistry/immunofluo...
The transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) controls differentiation of long-lived plasma cells, and almost 10% of individuals with common variable immunodeficiency (CVID) express either the C104R or A181E variants of TACI. These variants impair TACI function, and TACI-deficient mice exhibit a CVID-like disease. However, 1%-2% of normal individuals ha...
Common variable immunodeficiency (CVID) is an immunological disorder characterized by defective antibody production, recurrent infections, most notably of the respiratory tract, autoimmune phenomena and cancer. Some CVID patients may also present disturbances of the cellular immune response such as a decrease in the number and proportion of different lymphocyte populations, diminished lymphopro...
BACKGROUND/AIM The aim of this study is to establish follow-up protocols for adult patients with common variable immunodeficiency (CVID) in a recently founded adult immunology clinic in the Central Anatolia Region of Turkey, where a clinical immunology center for adults was not available previously. MATERIALS AND METHODS A total of 25 patients with CVID aged 18 years and older were included i...
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