BioSig3D is a computational platform for high-content screening of three-dimensional (3D) cell culture models that are imaged in full 3D volume. It provides an end-to-end solution for designing high content screening assays, based on colony organization that is derived from segmentation of nuclei in each colony. BioSig3D also enables visualization of raw and processed 3D volumetric data for qua...

succinate contained increasing amounts of wax as the specific growth rate decreased from 0.7h-I to 0.12h-I. The wax composition also varied with dilution rate, samples having a high wax content had palmitic acid and palmityl alcohol as major components. In continuous culture with succinate limitation and excess of nitrogen, the bacteria contained only small amounts of waxes, which increased sli...

Nitrogen fertilizer application rates in intensive agricultural systems have increased dramatically in recent years, especially in protected vegetable production systems. This excessive use of nitrogen fertilizer has resulted in soil secondary salinity, which has become a significant environmental stress for crops such as cucumber, in the protected farmlands. It is thus necessary to illuminate ...

Objective: This study aims to develop and create a tool based on factor analysis to assess safety culture in the processing industry. Methods: This study was conducted in the petrochemical industry in 2021. The questionnaires were distributed among 312 employees, supervisors, and managers, and 308 of them were completed. The validity of the questionnaire was assessed by content and construct v...

During intramembranous bone formation, preosteoblasts condense, differentiate into osteoblasts and deposit bone matrix. We compared the differentiation process of rat calvarial osteoblast-like cells inoculated as micromasses, which mimic the in vivo condensation process, with cells inoculated as monolayers. The cells were analysed morphologically at 1,2 and 3 weeks by light microscopy (alkaline...