Cholera toxin B subunit (CTB) is a mucosal immunomodulatory protein that induces robust mucosal and systemic antibody responses. This well-known biological activity has been exploited in cholera prevention (as a component of Dukoral® vaccine) and vaccine development for decades. On the other hand, several studies have investigated CTB's immunotherapeutic potential in the treatment of inflammato...

Three ferrous/ferric complexes of a N6 hexadentate ligand, N,N,N',N'-tetrakis(2-benzimidazolyl-methyl)ortho-diamine-trans-cyclohexane (ctb), [Fe(II)(ctb)](ClO(4))(2).EtOH (), [Fe(III)(OEt)(Hctb)](ClO(4))(3).EtOH (), and [Fe(III)(OMe)(Hctb)](ClO(4))(3).3MeOH.4.5H(2)O (), were synthesized and characterized as models of lipoxygenase. The lipoxygenase activities of the complexes were checked and th...

In the present article, cashew nut biocarbon (CTB), an agricultural waste, is used as reinforcement in Al6061 by heating process. The primary XRD study on CTB confirms presence of SiO2, Al2O3, iron-rich ferro-axinite, MgO, and Mn, which improve material’s properties when reinforcement. SiO2 levels increase with annealing time. extracted crushed into a ball mill for 24 hours, particle size measu...

We report on VHE γ-observations with the MAGIC telescope of the pulsar PSR B1951+32 and its associated nebula CTB 80. Our data constrain the cutoff energy of the pulsar to be < 32GeV, assuming the pulsed γ-ray emission to be exponentially cutoff. The upper limit on the flux of pulsed γ-ray emission > 75GeV is 4.3 · 10 photons cm sec and the upper limit on the flux of steady emission > 140GeV is...

Pipeline transportation is the key component of mine filling system. In this study, fresh cement tailing backfill (CTB) slurry made by unclassified tailings from Daye iron taken as research object, and its rheological parameters transport characteristics are studied via laboratory test FLUENT software. It was found that relationship curve dynamic yield stress, viscosity, solid content (SC) CTB ...

The upper cervical esophagus is exerted on swallowing and peristalsis by somatic and visceral motoneurons, whereas the lower esophagus is exerted on only peristalsis by visceral motoneurons. We examined the origin of the esophageal motoneurons and whether there were any differences between the distributions of the upper and the lower esophageal motoneurons in the medulla and the spinal cord usi...

  Background: CT scan and nuclear medicine exams deliver a great part of medical exposures. This study examined professional radiation hazards in CT scan and nuclear medicine workers.   Methods : In a cross sectional study 30 occupationally exposed workers and 7 controls (all from personnel of a laboratory) were selected. Physical dosimetry was performed for exposed workers. Blood samples were ...

Corn, one of the most important forage crops worldwide, has proven to be a useful expression vehicle due to the availability of established transformation procedures for this well-studied plant. The exotoxin Apx, a major virulence factor, is recognized as a common antigen of Actinobacillus (A.) pleuropneumoniae, the causative agent of porcine pleuropneumonia. In this study, a cholera toxin B (C...

We characterized penicillin-susceptible group B streptococcal (PSGBS) clinical isolates exhibiting no growth inhibition zone around a ceftibuten disk (CTB(r) PSGBS). The CTB(r) PSGBS isolates, for which augmented MICs of cefaclor and ceftizoxime were found, shared a T394A substitution in penicillin-binding protein 2X (PBP 2X) and a T567I substitution in PBP 2B, together with an additional G429S...