Techniques that originate in computer graphics and computer vision have found prominent applications in the medical domain. In this paper, we have seamlessly developed techniques from computer graphics and computer vision together with domain knowledge from medicine to develop an image guided surgical system for medialization laryngoplasty. The technical focus of this paper is to register the p...

Improving image quality is a critical objective in low dose computed tomography (CT) imaging and is the primary focus of CT image denoising. State-of-the-art CT denoising algorithms are mainly based on iterative minimization of an objective function, in which the performance is controlled by regularization parameters. To achieve the best results, these should be chosen carefully. However, the p...

Background Management of clinically node-positive bladder cancer (cN+ BC) is poorly defined; national guidelines recommend chemotherapy (CT) alone or chemoradiation (CRT). Objective Using a large, contemporary dataset, we evaluated national practice patterns and outcomes of CT versus CRT to elucidate the optimal therapy for this patient population. Methods The National Cancer Data Base (NCD...

In order to understand and to simulate the functional behaviour of porous structures during loading, quantitative knowledge of the relationship between the morphology and the mechanical behaviour is necessary. Therefore, the porous structures need to be quantified morphologically. In this research, the quantification will be performed by using micro-CT. However, to date, this technique encounte...

OBJECTIVE To explore semantic search to improve management and user navigation in clinical archetype repositories. METHODS In order to support semantic searches across archetypes, an automated method based on SNOMED CT modularization is implemented to transform clinical archetypes into SNOMED CT extracts. Concurrently, query terms are converted into SNOMED CT concepts using the search engine ...

We present a quantitative model to analyze the detrimental effects of for edema on the quality of prostate brachytherapy implants We account for both tissue expansion and implant migration by mapping intra-operative ultrasound and post-implant CT. We pre-process the ultrasound with a phase congruency filter, and map it to the volume CT using a B-spline deformable mutual information similarity m...

With electronic health records rising in popularity among hospitals and physicians, the SNOMED CT medical terminology has served as a valuable standard for those looking to exchange a variety of information linked to clinical knowledge bases, information retrieval, and data aggregation. However, SNOMED CT is distributed as a flat file database by the International Health Terminology Standards D...

We developed an automated system for registering computed tomography (CT) images of the chest temporally. Our system detects anatomical landmarks, in particular, the trachea, sternum and spine, using an attenuation-based template matching approach. It computes the optimal rigid-body transformation that aligns the corresponding landmarks in two CT scans of the same patient. This transformation t...

We evaluated whether donor computed tomography (CT) with a combined technique of lower tube voltage and iterative reconstruction (IR) can provide sufficient preoperative information for liver transplantation.We retrospectively reviewed CT of 113 liver donor candidates. Dynamic contrast-enhanced CT of the liver was performed on the following protocol: protocol A (n = 70), 120-kVp with filtered b...

many large oil and gas fields in the most productive world regions happen to be fractured. the exploration and development of these reservoirs is a true challenge for many operators. these difficulties are due to uncertainties in geological fracture properties such as aperture, length, connectivity and intensity distribution. to successfully address these challenges, it is paramount to improve ...