BACKGROUND/AIMS Liquid nitrogen spray freezing has been successfully applied for basal cell carcinomas in the eyelid region, but is not yet in general use. The reasons for this were analysed and the development of a more reliable, safer cryosurgical technique aimed for. METHODS New cryosurgical apparatus, contact probes with increased freezing power, and a special application technique were d...

Since the 1920s the gold standard for treating cancer has been surgery, which is typically preceded or followed with chemotherapy and/or radiation, a process that perhaps contributes to the destruction of a patient’s immune defense system. Cryosurgery ablation of a solid tumor is mechanistically similar to a vaccination where hundreds of unique antigens from a heterogeneous population of tumor ...

To explain the mechanism of action of a novel intralesional cryoprobe, thermal behavior measurements, and histological studies were performed in swine muscle specimens after intralesional cryosurgery ex vivo. Slow cooling (20 degrees C/min) and thawing (25 degrees C/min) rates, end temperature of -30 degrees C, produced 8 mm wide diffuse coagulative-type necrosis and a 3 mm-wide transition zone...

BACKGROUND Cryosurgery is one of the simplest, most effective gingival depigmentation methods. Repigmentation may happen after a while in each method. The aim of this study is to compare the recurrence rate after treatment by liquid nitrogen swap and a cryoprob in 18 months. MATERIALS AND METHODS A total of 26 patients with physiologic gingival pigmentation were selected. The anterior sextant...

For decades, many techniques have been developed for curing cancer. Cryosurgery is one of such processes destroying tumors by inserting a cryoprobe into the target region which connected to cryogenic mechanism. Presently, this technique used only simple tumors. Hence, work aims trigger toward large-sized internal The main objectives are (1) identify mechanical and thermal behavior tumor tissue ...