Dextran, a family of natural polysaccharides, consists of an α (1→6) linked-glucose main (backbone) chain having a number of branches. The determination of the types and the quantities of branches in dextran is important in understanding its various biological roles. In this study, a hyphenated method using high-performance anion exchange chromatography (HPAEC) in parallel with pulsed amperomet...

Microspheres of Trimetazidine Hydrochloride (TZ) were prepared by coacervation method without the use of chemical cross–linking agents such as glutaraldehyde to avoid the toxic reactions and other undesirable effects of the chemical cross-linking agents. Alternatively, ionotropic gelation was employed by using sodium-tripolyphosphate (Na-TPP) as cross linking agent. Chitosan was used as polymer...

shown by demonstrating that the overall rate of dextransucrase synthesis is independent of the concentration of 1,6-linked dextran acceptor if synthesis is continued for periods that are directly proportional to the amount of acceptor present. For example, in the presence of 1 mg of acceptor dextran, the rate of dextransucrase action measured over lOmin is identical with the rate measured over ...

in the present study, the production of dextran from date extract and sucrose as carbon sources by the bacterium leuconostoc mesenteroides nrrl b512 (f) was investigated. in comparison to blue dextran (mw≈2000 da), dextran molecular weight was reduced (mw2000 kda). flow behavior indices of dextran solutions from date extracts were investigated and rheological parameters were evaluated at concen...

The output colour distributions from red, green and blue (RGB) LEDs mixed with cross linked PMMA micro particle doped PMMA mixing rods is compared to output from a plain PMMA mixing rod. Distinctive patterns with clear colour separation result with the undoped rod. These are homogenised by our mixers, resulting in white light. Light output has been photographed, measured and computer simulated ...

The objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (MA) using two polymers with different characteristics as ethylcellulose (EC) and/or cellulose acetate phthalate (CAP). Microspheres were prepared by the modified emulsion solvent evaporation (MESE). The effect of drug-polymer interaction was studied for each of microspheres. Important param...

A novel strategy was developed to synthesize uniform semi-interpenetrating polymer network (semi-IPN) microspheres by premix membrane emulsification combined with one-step polymerization. Synthesized poly(acrylic acid) (PAAc) polymer chains were added prior to the inner water phase, which contained N-isopropylacrylamide (NIPAM) monomer, N,N1-methylene bisacrylamide (MBA) cross-linker, and ammon...

Objectives: The purpose of this research work was to formulate and systemically evaluate in vitro performances polymeric microspheres nifedipine. Methods: Nifedipine containing two polymers, poloxamer 407 carbopol 934, were prepared by single emulsion cross-linking technique. Glutaraldehyde selected as the agent. A Box–Behnken design employed study effect independent variables, polymer concentr...

The effect of magnetic interactions on the Brownian motion of two magnetic microparticles is investigated. The cross-correlations of the thermal fluctuations of the two magnetic microbeads are directly measured using double-trap optical tweezers. It is experimentally demonstrated that the cross-correlation function is governed by the gradient of the magnetic force between the microparticles. Th...