BACKGROUND Hormone-sensitive lipase (HSL) is expressed predominantly in adipose tissue, where it plays an important role in catecholamine-stimulated hydrolysis of stored lipids, thus mobilizing fatty acids. HSL exhibits broad substrate specificity and besides acylglycerides it hydrolyzes cholesteryl esters, retinyl esters and lipoidal esters. Despite its role in fatty acid mobilization, HSL nul...

Die funksies van die verpleegkundige kan beskou word as synde afhanklik, interafhanklik en onafhanklik. Die tradisionele beskouing van die betekenis van veral die aflianklike funksie word egter bevraagteken vanuit die wetlike en etiese perspektiewe wat in Suid-Afrika geld. Omdat die verpleegkundige verantwoordelik en aanspreeklik is vir alles wat sy doen of laat is haar funksie slegs af­ hankli...

The development of Insulin resistance in obesity is associated with infiltration of immune cells in white adipose tissue (WAT). Especially macrophage infiltration in WAT is known to produce several proinflmmatory cytokines which induces the state of inflammation and impairs the insulin signaling and related pathways. Several animal and human studies have been conducted to unravel the mystery of...

Professionele ontnugtering by die studentverpleegkundige, wat ’n belangrike rede vir beroepsverlating is, was die onderwerp van hierdie navorsing onder studente in die Oos-Kaap. Een van die belangrikste redes vir professionele ont­ nugtering is gebrekkige sosialisering van die student in die beroep. Die voigende faktore wat met professionalisering en sosialisering verband hou is ontleed: die in...

Many of the herbaceous perennials, especially the newer cultivars of Echinacea, are poorly branching, slow to fill out the pot, and produce few propagules. Configure (6-BA, Fine Americas, Inc.), a new product recently labeled for branching of floricultural crops, was evaluated on a variety of perennials over two seasons. Configure was applied once as a foliar spray at rates of 0, 300, 600, 900 ...

Invasive plants degrade aquatic ecosystems throughout the United States. These weedy species destroy fish and wildlife habitat and interfere with water uses and ecological processes. Currently, there are only eight herbicides labeled for use in aquatic sites. In order to control newly introduced invasive plants and implement resistance management stewardship, additional chemistries and active i...

OBJECTIVE A potential strategy to treat obesity - and the associated metabolic consequences - is to increase energy expenditure. This could be achieved by stimulating thermogenesis through activation of brown adipose tissue (BAT) and/or the induction of browning of white adipose tissue (WAT). Over the last years, it has become clear that several metalloproteinases play an important role in adip...