The blood of Limulus polyphemus L. has been shown to contain the protein haemocyanin and white corpuscles. The blood clots with great rapidity. Loebl found that clotting is not preventable by the usual chemical methods but only by methods which prevent agglutination of the corpuscles. Further, Loeb has shown that the clot is formed by the agglutination of the corpuscles, indicating the absence ...

The life of Filippo Pacini (1812-1883) and his major scientific achievements are outlined. Pacini drew attention to the corpuscles named after him in 1831, when he was a medical student, and had to struggle for many years to convince the scientific community of the reliability and importance of his findings. In 1849 Pacini became professor of anatomy at the University of Florence. Creative scie...

Responses were recorded from cutaneous afferents innervating mechanoreceptors in the monkey's fingerpad, while gratings of alternating grooves and ridges were moved sinusoidally across their receptive fields. The gratings were specified by their spatial period and the movement by its peak speed: together these determined the peak temporal frequency at which grating ridges passed over the recept...

Responses were recorded from cutaneous afferents innervating mechanoreceptors in the monkey's fingerpad. When gratings of alternating grooves and ridges were moved sinusoidally back and forth across the receptive field, the responses of the afferent were often not equal for the 2 directions of movement. To investigate this phenomenon, the position of the center of the afferent's receptive field...

Field and Teague 1 have recently shown that toxins and antitoxins under the influence of the electric current migrate toward the cathode, and in a second series of experiments they found that the agglutinins of typhoid immune serum also travel toward the cathode. With hemolysins the conditions are somewhat more complicated than with toxins or agglutinins owing to the presence of two factors, am...

Golgi tendon organs and Pacinian corpuscles are peripheral mechanoreceptors that disappear after denervation during a critical period in early postnatal development. Even if regeneration is allowed to occur, Golgi tendon organs do not reform, and the reformation of Pacinian corpuscles is greatly impaired. The sensory nerve terminals of both types of mechanoreceptors are closely associated with ...