artery, and it has been suggested that these patients should be treated by bypass surgery. The mechanism for sudden death is not known. Theories include kinking of the anomalous artery2 and occlusion by a flap-like closure of the ostium as the aorta expands.3 However, sudden death, infarction, and ischemia may occur without regard to the course of the anomalous left coronary artery.4 In the pas...

In 26 patients having coronary grafts, haemodynamics, coronary sinus blood flow and the arterio-coronary sinus difference of oxygen content were determined, awake and at four intervals during morphine-oxygen or halothane--oxygen anaesthesia. Rate-pressure product (RPP), triple product (TP) and myocardial oxygen consumption (MVO2) were calculated. The correlation of the two indirect indices to M...

BACKGROUND The addition of a mitral isthmus (MI) block line after pulmonary vein isolation could lead to a favorable outcome of catheter ablation in patients with atrial fibrillation (AF). However, it is sometimes tough to create a complete MI block line, and the cooling effect because of the local coronary flow may prevent the creation of a successful MI block line. METHODS AND RESULTS This ...

We evaluated the effects of sublingual nitroglycerin on indices of regional coronary flow and coronary resistance (CR) in 12 selected patients with coronary artery disease (CAD) and eight with normal coronary arteries (NCA), using continuous thermodilution. Resting total left ventricular flow, reflected by coronary sinus flow (CSF), and anterior regional flow, reflected by great cardiac vein fl...

Coronary sinus (CS) is a landmark for cardiac intervention. Before catheter ablation of paroxysmal supraventricular tachycardia, coronary sinus is used to obtain recordings from the left atrium and ventricle. Despite asymptomatic, anomalies of coronary sinus may become an obstacle for electrophysiological catheterization. Here, we described a case of successful ablation of paroxysmal supraventr...

Background: Anomalous origin of the right coronary artery from left sinus Valsalva (ARCA) is a rare anomaly. Surgery recommended in symptomatic patients, while optimal surgical approach controversial.
 Case presentation: We present case an ARCA 56-year-old male who was managed with bypass grafting using internal mammary and ligation proximal artery. The patient remained asymptomatic after ...

Oxygen in high concentration (arterial P02 over 400 mm Hg), administered for 7-10 minutes to six subjects with normal coronary arteries and nine subjects with coronary artery disease caused the following significant changes: The heart rate and cardiac index decreased in both groups. The mean arterial pressure increased in the coronary group. The coronary sinus blood flow fell from 158 11 (mean ...

Previous studies have demonstrated competition between sympathetic alpha receptor-mediated coronary vasoconstriction and local metabolic vasodilation during sympathetic activation. The present study tested if this competition also occurs in the presence of coronary stenosis. In closed-chest dogs, the left coronary artery was cannulated, and blood flow from the aorta was restricted by a moderate...

BACKGROUND The effects of cocaine on the coronary circulation were examined in conscious dogs chronically instrumented to measure arterial and left ventricular pressures, coronary blood flow, and arterial and coronary sinus oxygen content. METHODS AND RESULTS With heart rate held constant, the peak effects of cocaine (1 mg/kg i.v.) occurred within 2 minutes, when mean arterial pressure increa...