BACKGROUND AND PURPOSE Myocardial infarction (MI) is the leading cause of long-term mortality in patients with stroke, yet the prevalence of coronary atherosclerosis in these individuals is unknown. The objective of the study was to establish the prevalence of coronary atherosclerosis and MI after fatal stroke. METHODS Using an autopsy data bank, we studied the prevalence of coronary plaques ...

background: the study of the association between genotype and phenotype is of great importance for the prediction of many diseases and pathophysiological conditions. the relationship between angiotensin-converting enzyme (ace) gene insertion/ deletion (i/d) polymorphism and pathological processes such as coronary artery disease (cad) has been investigated previously with discordant results. thi...

PET provides robust and reproducible measurements of regional myocardial blood flow in milliliters per minute per gram of tissue, providing unique pathophysiologic and diagnostic information on the function of the coronary macro- and microcirculation. There is compelling evidence to suggest that in many instances abnormalities of global myocardial perfusion are demonstrated in individuals with ...

Coronary artery disease causes acute myocardial infarction and heart failure. Identifying coronary vascular progenitors and their developmental program could inspire novel regenerative treatments for cardiac diseases. The developmental origins of the coronary vessels have been shrouded in mystery and debated for several decades. Recent identification of progenitors for coronary vessels within t...

Background: Monocytes are essential components in inflammatory signaling, and their recruitment is crucial the signaling pathway, which directs determines cell adhesion to activated endothelium. A better understanding of correlation between monocyte subsets patients with atherosclerotic disease acute coronary syndrome (ACS) for development more effective therapies prevention treatment cardiovas...

Coronary heart disease (CHD) is a generic designation for group of related syndromes resulting from myocardial ischemia – an imbalance between cardiac blood supply (perfusion) and oxygen demand. Visfatin (VF) recently discovered adipokine with different functions, mainly found in visceral adipose tissue mimics insulin lowering plasma glucose levels and, emerges as player the development progres...