PURPOSE To investigate the diagnostic accuracy and limitations of 16-slice multidetector computed tomography (MDCT) in the detection of significant ( > 50%) stenosis of coronary artery bypass grafts (CABG) and native coronary arteries. MATERIALS AND METHODS One hundred two patients with 236 grafts were investigated by 16-slice MDCT. Native coronary arteries were also investigated. The image q...

objectives: coronary artery disease (cad) is caused by atherosclerosis in coronary arteries and results in cardiac arrest and heart attack. angiography is one of the most accurate methods to diagnose heart disease, it incurs high expenses and comes with side effects. data mining is the extraction of hidden predictive information and unknown data, patterns, relationships and knowledge by explori...

Background Atherosclerotic coronary artery disease remains a major cause of illness and death, and coronary flow predetermines disease. Limitations in imaging technology prevent coronary flow measurements but computational fluid dynamics (CFD) need sophisticated boundary conditions for accurate flow predictions. MRI has recently been combined with CFD for larger calibre vessels, but small coron...

Background and aims Novel genetic determinants associated with coronary artery disease (CAD) have been discovered by genome wide association studies. Variants encompassing the CELSR2- PSRC1-SORT1 gene cluster CAD. This study is aimed to investigate rs629301 polymorphism extent of CAD evaluated angiography (CAG), evaluate its associations an extensive panel lipid lipoprotein measurements in a la...

One hundred and forty-nine patients with suspected ischaemic heart disease were evaluated by exercise thallium-201 myocardial scintigraphy (201Tl SMS), single lead exercise electrocardiography, and coronary arteriography. Myocardial distribution of tracer was assessed semi-quantitatively from digital 201Tl scintigrams and compared with tracer distribution in subjects with normal hearts. Fifty-t...

BACKGROUND Coronary arteries without focal stenosis at angiography are generally considered non-flow-limiting. However, atherosclerosis is a diffuse process that often remains invisible at angiography. Accordingly, we hypothesized that in patients with coronary artery disease, nonstenotic coronary arteries induce a decrease in pressure along their length due to diffuse coronary atherosclerosis....

A 44 years old male patient with acute coronary syndrome and polycystic kidney disease is described. Coronary angiography showed ectatic coronary arteries. Polycystic kidney disease is the most common inherited kidney disorder which is commonly associated with extra renal manifestations including cardiovascular conditions. Involvement of vessels may lead to arterial aneurysms which most commonl...

OBJECTIVES This study sought to analyze the effect of short-term transdermal estradiol treatment on in vivo coronary endothelial function in postmenopausal women with angina and normal results on coronary arteriograms. BACKGROUND The incidence of coronary heart disease increases in women after menopause. Estrogen replacement therapy has been associated with a global reduction in cardiovascula...

Background: Coronary angiography consists of the selective injection of contrast agents in coronary arteries. Optimal strategy for heparin administration during coronary angiography has yet to be determined. We assessed the effect of heparin administration during coronary angiography on vascular, hemorrhagic, and ischemic complications.Methods: Five hundred candiates for diagnostic coronary ang...

objectives to evaluate predictive value of vessel specific coronary artery calcium (cac) score in predicting obstructive coronary artery disease. patients and methods in this diagnostic test study we evaluated patients with coronary computed tomography angiography (ccta) and cac score which had been referred to two referral radiology center in tehran, iran and finally we selected 2525 patients ...