BACKGROUND Coronary artery disease (CAD) is associated with the numbers of risk factors causing coronary atherosclerosis. Coronary artery stenosis is mostly caused by coronary atherosclerosis. OBJECTIVE This study aims to analyze the association between coronary artery stenosis and cardiovascular risk factors. METHODS An observational study was conducted among CAD patients. The diagnostic c...

background and objectives: cardiovascular disease is the most common cause of death in developed countries. in addition to traditional risk factors for cardiovascular disease, nowadays, accumulating evidence indicates that a variety of infections contribute to pathogenesis of atherosclerosis,  (we investigated whether helicobacter pylori infection is related to prevalence of coronary heart dise...

Paraoxonase1 (PON1) activity is closely related to coronary artery disease (CAD). However, whether PON1 activity can predict the degree of coronary stenosis remains unknown. In the present study, the serum PON1 activity and related factors that influence PON1 activity were analyzed in 186 patients with diagnostic coronary angiography. The serum PON1 activity was determined using a spectrophotom...

A 64-year-old man was evaluated for atypical chest pain that was present during transurethral prostatectomy. He had no risk factors for coronary artery disease (CAD), no prior history of ischaemic heart disease and had not experienced any symptoms of chest pain during exercise before. Computed tomography coronary angiography (CTCA) was performed to exclude CAD. CTCA (Fig. 1) showed a normal rig...

BACKGROUND Atherosclerosis is a chronic inflammatory process resulting in coronary artery disease. OBJECTIVES To determine the relationship between inflammatory markers and the angiographic severity of CAD. METHODS We measured inflammatory markers in consecutive patients undergoing coronary angiography. This included C-reactive protein, fibrinogen, serum cytokines (interleukin-1 beta, IL-1 ...

OBJECTIVES The aim of this project was to assess the utility of dobutamine stress echocardiography (DSE) for evaluation of women with suspected ischemic heart disease. BACKGROUND Most investigations addressing efficacy of diagnosis and treatment of coronary artery disease (CAD) have been performed in predominantly male populations. As part of the Women's Ischemia Syndrome Evaluation (WISE) st...

objective(s): apolipoprotein e genotype (apoe) polymorphism affects lipid levels and coronary artery disease (cad) risk. the aim of this study was to study the association of the apolipoprotein e genotypes with coronary artery disease in the iranian population.   materials and methods: the apolipoprotein e genotype in dna samples extracted from 66 cad+ patients and 61 control subjects by restri...

Congenital coronary artery anomalies are of major significance in clinical cardiology and cardiac surgery due to their association with myocardial ischaemia and sudden death. Such anomalies are detectable by imaging modalities and, according to various definitions, their prevalence ranges from 0.21 to 5.79%. This consensus document from the Development, Anatomy and Pathology Working Group of th...

Coronary artery aneurysm (CAA), defined as dilatation of the coronary artery exceeding 50% of the reference vessel diameter, is uncommon and occurs in 5% of coronary angiographic series.1 CAAs are termed giant if their diameter exceeds the reference vessel diameter by 4 times or if they are 8 mm in diameter.2 Atherosclerosis accounts for the vast majority of CAAs in adults, whereas Kawasaki dis...

Coronary anomalies affect a small percentage of the general population. A solitary coronary ostium in the absence of other major congenital anomalies is very rare. We describe a case of a patient, admitted to our cardiology department with an acute myocardial infarction. A coronary angiogram shows a solitary ostium originating from the right sinus of Valsalva with the left anterior descending c...