نتایج جستجو برای: corneal endothelial cell

تعداد نتایج: 1780581  

2018
Sergi Segarra Marta Leiva Daniel Costa Natàlia Coyo Maria Sabés-Alsina José Ríos Teresa Peña

BACKGROUND Rabbits are currently not a good model for studying diseases of the corneal endothelium because their corneal endothelial cells (CECs) maintain a high proliferative capacity throughout almost all their life. Addressing this particular feature might allow the use of this species for such a purpose. The aim of this study was to evaluate the corneal endothelial injury after intracameral...

Journal: :Investigative ophthalmology & visual science 1986
C F Bahn R M Glassman D K MacCallum J H Lillie R F Meyer B J Robinson N M Rich

Comparison specular micrographs of infant and adult corneas from cats, cows, dogs, rabbits, and humans demonstrate that a large decrease in central endothelial cell density occurs during maturation of the cornea. Central endothelial cell counts of developing cat, dog, and rabbit corneas decrease rapidly during the first months of life. This rapid decline in endothelial cell density correlates w...

Journal: :Investigative ophthalmology 1976
B E McCarey F M Polack W Marshall

Irrigating solutions for intraocular purposes were evaluated for their possible damaging effects on the corneal endothelial cell structure and function. Rabbit corneal endothelium was perfused in vitro with Tis-u-Sol, Travenol Ringer's Solution, or Travenol Sodium Chloride. The irrigating solutions caused an immediate corneal swelling of 67 mum per hour +/- 5 (mean +/- standard error), which wa...

Journal: :Cornea 2001
C Yap A M Wong J Naor D S Rootman

PURPOSE To compare corneal endothelial cell function by measuring corneal thickness during temperature reversal between corneas stored in two different storage media, Optisol GS and Chen Medium (CM). METHODS Twenty paired corneas from 10 human donors were randomly assigned for storage at 4 degrees C in Optisol GS (10 corneas) or CM (10 corneas). The storage media were masked, and measurements...

Journal: :Human molecular genetics 2001
S Biswas F L Munier J Yardley N Hart-Holden R Perveen P Cousin J E Sutphin B Noble M Batterbury C Kielty A Hackett R Bonshek A Ridgway D McLeod V C Sheffield E M Stone D F Schorderet G C Black

Corneal clarity is maintained by its endothelium, which functions abnormally in the endothelial dystrophies, leading to corneal opacification. This group of conditions includes Fuchs' endothelial dystrophy of the cornea (FECD), one of the commonest indications for corneal transplantation performed in developed countries, posterior polymorphous dystrophy (PPCD) and the congenital hereditary endo...

2014
Claude J. Giasson Alexandre Deschambeault Patrick Carrier Lucie Germain

PURPOSE To test whether adherens junction proteins are present in the epithelium and the endothelium of corneal equivalents. METHODS Corneal cell types were harvested from human eyes and grown separately. Stromal equivalents were constructed by seeding fibroblasts into a collagen gel on which epithelial and endothelial cells were added on each side. Alternatively, bovine endothelial cells wer...

Journal: :Journal of Korean Medical Science 1992
H. Tchah

A heterologous corneal endothelial transplantation was attempted using human endothelial cells and a Lewis rat penetrating keratoplasty model. Cultured human endothelial cells were seeded to a Lewis rat cornea, which was denuded of its endothelium. When grafted into the syngeneic Lewis rat, the graft remained clear for at least five days, and then became opaque and edematous because of immune r...

Journal: :Archives of ophthalmology 2009
Norihiko Honda Tatsuya Mimura Tomohiko Usui Shiro Amano

OBJECTIVE To investigate the feasibility of Descemet stripping automated endothelial keratoplasty (DSAEK) using cultured human corneal endothelial cells (HCECs) in an animal model. METHODS Descemet stripping automated endothelial keratoplasty grafts were produced by seeding cultured HCEC suspensions onto human corneal stromal discs. Three insertion techniques were assessed in an ex vivo model...

2015
Masahito Yoshihara Hiroko Ohmiya Susumu Hara Satoshi Kawasaki Yoshihide Hayashizaki Masayoshi Itoh Hideya Kawaji Motokazu Tsujikawa Kohji Nishida

The corneal endothelium is a monolayer of hexagonal corneal endothelial cells (CECs) on the inner surface of the cornea. CECs are critical in maintaining corneal transparency through their barrier and pump functions. CECs in vivo have a limited capacity in proliferation, and loss of a significant number of CECs results in corneal edema called bullous keratopathy which can lead to severe visual ...

ژورنال: بینا 2019
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Purpose: To investigate the effect of smoking on corneal parameters, including Endothelial Cell Density, Central Corneal Thickness, Percent of Hexogonality, and Coefficient of Variation. Methods: This study was a systematic review and meta-analysis of published articles until the end of February 2019. To do this, the first search was done for creditable medical databases such as PubMed, and ISI...

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