Purpose: Homeostasis and control of the intracellular calcium concentration are critical for multiple physiological and functional processes in neurons as well as for neuronal viability. Inositol–1, 4, 5–trisphosphate(IP3) receptors (IP3Rs) are major intracellular calcium channels releasing calcium from intracellular stores, such as the endoplasmic reticulum, and contribute to calcium–mediated ...

Verbal reports of loss of control and surrender to powerful visual changes, experienced during inversion of the visual world, seemed to be suggestive of changes in field dependence. Field dependence (rod-and-frame test vertical) was tested under conditions of inversion and noninversion. Significantly greater field dependence was observed for subjects exposed to complete inversion rotation of th...

BACKGROUND This study was designed to investigate the effect of BMSCs transfected BMP-2 composite with magnesium alloy rod in the repair of the femoral head necrosis in New Zealand white rabbits. Multifactorial but mostly traumatic, osteonecrosis of the femoral head account for 10 % of the 250,000 total hip arthroplasties done annually in the United States while its prevalence in most countries...

Idiopathic osteoporosis (IOP) in premenopausal women is a poorly understood entity in which otherwise healthy women have low-trauma fracture or very low bone mineral density (BMD). In this study, we applied individual trabeculae segmentation (ITS)-based morphological analysis to high-resolution peripheral quantitative computed tomography (HR-pQCT) images of the distal radius and distal tibia to...

Cell shape in most eubacteria is maintained by a tough external peptidoglycan cell wall. Recently, cell shape determining proteins of the MreB family were shown to form helical, actin-like cables in the cell. We used a fluorescent derivative of the antibiotic vancomycin as a probe for nascent peptidoglycan synthesis in unfixed cells of various Gram-positive bacteria. In the rod-shaped bacterium...

The authors examined anticipation in tool use, focusing on tool length and tool-use posture. Adults (9 women and 9 men in each experiment) held a rod (length 0.4-0.8 m), with the tip upward; walked toward a cube; chose a place to stop; and displaced the cube with the rod's tip. In 2 experiments, rod length, mass, and mass distribution, and the size of the cube were manipulated. Chosen distance ...

A system using microgripper for gluing and adhesive bonding in automatic microassembly was designed, implemented, and tested. The development of system is guided by axiomatic design principle. With a compliant PU microgripper, regional-edge-statistics (RES) algorithm, and PD controller, a visual-servoing system was implemented for gripping micro object, gluing adhesive, and operating adhesive b...

In cell-extracellular matrix junctions (focal adhesions), the cytoskeletal protein talin is central to the connection of integrins to the actin cytoskeleton. Talin is thought to mediate this connection via its two integrin, (at least) three actin, and several vinculin binding sites. The binding sites are cryptic in the head-to-rod autoinhibited cytoplasmic form of the protein and require (stepw...

We make two remarks about the null-controllability of the heat equation with Dirichlet condition in unbounded domains. Firstly, we give a geometric necessary condition (for interior null-controllability in the Euclidean setting) which implies that one can not go infinitely far away from the control region without tending to the boundary (if any), but also applies when the distance to the contro...