The crystal structure of the six NH2-terminal zinc fingers of Xenopus laevis transcription factor IIIA (TFIIIA) bound with 31 bp of the 5S rRNA gene promoter has been determined at 3.1 A resolution. Individual zinc fingers are positioned differently in the major groove and across the minor groove of DNA to span the entire length of the duplex. These results show how TFIIIA can recognize several...

For corrugated pipes with a square groove, it is known that there no interaction between the main flow and groove when aspect ratio less than four. When length height are different, occurs in pipe. In previous studies, was investigated whether this dependent on length. However, changing height, shape of vortex generated inside changes, which may cause to occur. Therefore, paper both as well pit...

The iconic helical structure of DNA is stabilized by the solvation environment, where a change in the hydration state can lead to dramatic changes to the DNA structure. X-ray diffraction experiments at cryogenic temperatures have shown crystallographic water molecules in the minor groove of DNA, which has led to the notion of a spine of hydration of DNA. Here, chiral nonlinear vibrational spect...

A microfiber is used as a laser-focusing unit to fabricate a groove structure on TiAlSiN surfaces. After one laser pulse etching, a groove with the minimum width of 265 nm is manufactured at the area. This technique of microfabricating the groove in microscale is studied. Based on the near-field intensity enhancement at the contact area between the fiber and the surface during the laser irradia...

Background: Genu valgum usually originates from a deformity of distal femur that is often corrected by distal femoralvarus osteotomy. The osteotomy includes both components of angulationcorrection and translation because the siteof osteotomy is not commonly at the apex of deformity. Improvement of patellar tracking not only depends on valguscorrection, but also it may be partially due to centra...