A new signal amplification strategy based on simultaneous application of gold nanoparticles (AuNPs) and horseradish peroxidase (HRP) was employed to improve the sensitivity of an electrochemical immunoassay for detection of human IgG (hIgG), as a model antigenic protein. This immunoassay system was fabricated on magnetic carboxyl-functionalized multi-walled carbon nanotubes (COOH-MWCNT/Fe3...

The transport properties of metal–molecule–metal junctions containing a monolayer of conjugated and saturated molecules with characteristic dimensions in the range 30–300 nm are correlated with microscopic topography, stress and chemical bonding at the metal–molecule interfaces. Our statistically significant dataset allows us to conclude that the conductivity of organic molecules ∼1.5 nm long i...

A review of nonequilibrium electronic transport in molecules and molecular-scale synthetic systems is given. Although the basic concepts and mechanisms for electronic conduction in polymers have been discussed for some time, recently developed experimental techniques provide systems for their validation. New fabrication techniques that create metallic contacts to a small number of conjugated or...

This study details a modular and general synthesis of a new class of molecules consisting of cruciform pi-systems. The key to synthesizing these molecules was an unprecedented double Staudinger cyclization. Once formed, these rigid compounds assemble into ordered monolayer films on metal and metal oxide surfaces to orient their conjugated, bis-phenyloxazole subunits upright. This surface orient...

There is a high degree of interest in organic thin films for lightweight, low power, rugged and flexible electronics. Conjugated organic molecules with polycyclic rings are being considered a major enabler of such applications. Due to a surface tension mismatch between the organic molecule with the inorganic support (mainly silicon oxides), molecular packing inside these thin films is often dis...

Abstract The unique specificity of DNA interactions and our ability to synthesize artificial functionalized sequences makes it the ideal material for controlling self-assembly chemical reactions components attached sequences. Inspired by field molecular electronics lack methods assemble components, we have explored organization conjugated using DNA-based self-assembly. In this chapter, provide ...

A selection of cyclic and acyclic acetylenic scaffolds bearing two tetrathiafulvalene (TTF) units was prepared by different metal-catalyzed coupling reactions. The bridge separating the two TTF units was systematically changed from linearly conjugated ethyne, butadiyne and tetraethynylethene (trans-substituted) units to a cross-conjugated tetraethynylethene unit, placed in either acyclic or cyc...

Site-specific mutation was demonstrated in a shuttle vector system using nitrogen mustard-conjugated oligodeoxyribonucleotides (ODNs). Plasmid DNA was modified in vitro by ODNs containing all four DNA bases in the presence of Escherichia coli RecA protein. Up to 50% of plasmid molecules were alkylated in the targeted region of the supF gene and mutations resulted upon replication in mammalian c...

Coordination between boron Lewis acid and nitrogen base (B?N) is a classically chemical issue that has been known for several decades. Recently, this B?N chemistry developed into new stage toward electronic materials, e.g., adjusting optoelectronic properties of N-based conjugated molecules via adding B acids, synthesizing B?N-bridged units, further constructing B?N-embedded organic photovoltai...

New photovoltaic (PV) energy technologies can contribute to environmentally friendly, renewable energy production, and the reduction of the carbon dioxide emission associated with fossil fuels and biomass. One new PV technology, plastic solar cell technology, is based on conjugated polymers and molecules. Polymer solar cells have attracted considerable attention in the past few years owing to t...