The aging of the human population made the number of bone fractures due to osteoporosis increase considerably. In Switzerland, the risk for an osteoporotic fracture in women above 50 years is about 50%, for men the risk is about 20%1. Not surprisingly, research concerning osteoporosis plays a prominent role in health science. Often, large scale computer simulations are conducted to improve the ...

introduction fracture - dislocations of the talus are typically due to high energy injuries. displaced fracture - dislocations of the talus have poor outcomes in general and complications are common. although talar fracture is common and comprises the second most common tarsal fracture, bilateral fracture - dislocations of the talus are rare. not many reports regarding the subject can be found ...

in this paper, the conjugate gradient method coupled with adjoint problem is used in order to solve the inverse heat conduction problem and estimation of the time- dependent heat flux using the temperature distribution at a point in a three layer system with none homogeneous boundary conditions. also, the effect of noisy data on final solution is studied. for solving this problem the general co...

the effect of boundary conditions on the solution of the inverse problem of identifying the geometry and location of a cavity inside an elastic solid body using displacement measurements obtained from a tension test is investigated. the boundary elements method (bem) coupled with the genetic algorithm (ga) and the conjugate gradient method (cgm) are implemented in this identification problem. a...

in this paper, we present an analytical method for solving a well-posed boundary value problem of mathematical physics governing the vibration characteristics of an internal flow propelled fluid-structure interaction where the pipeline segment is idealized as an elastic hollow beam conveying an incompressible fluid on a viscoelastic foundation. the effect of coriolis and damping forces on the o...

a new efficient method for the synthesis of carboacyclic nucleosides as biologically interesting compounds via aza-conjugate addition of pyrimidine nucleobases to a,β-unsaturated esters in the presence of catalytic amount of lioh.h2o (1.2-4.8 mol%) under microwave irradiation is described. this method affords the title compounds in good to excellent yields and in short reaction times.

This tutorial describes the classic method of conjugate directions: the generalization of the conjugate-gradient method in iterative least-square inversion. I derive the algebraic equations of the conjugate-direction method from general optimization principles. The derivation explains the “magic” properties of conjugate gradients. It also justifies the use of conjugate directions in cases when ...

Levels of the phytohormone indole-3-acetic acid (IAA) can be altered by the formation and hydrolysis of IAA conjugates. The isolation and characterization of Arabidopsis thaliana mutants with reduced IAA-conjugate sensitivity and wild-type IAA responses is advancing the understanding of auxin homeostasis by uncovering the factors needed for conjugate metabolism. For example, the discovery that ...

Photodynamic therapy has been applied quite extensively over the last few years, whereby the activation of photosensitizers by light causes the production of reactive oxygen species such as singlet oxygen, which is cytotoxic. The goal of this study was the enhancement of the photodynamic activity of photosensitizers through their delivery to specific, sensitive intracellular compartments of tar...

 We present an exceedingly rare case of left Monteggia-Galeazzi fracture-dislocation and right Monteggiadistal radius fracture occurring simultaneously in a 20-year old male patient who had fallen 13 meters from a building. The combination of Monteggia and Galeazzi fracture-dislocation in the same forearm is very rare and, to the best of our knowledge, simultaneous bilateral Monteggia and Galea...