نتایج جستجو برای: congenital generalized lipodystrophy

تعداد نتایج: 286938  

اخی , عذرا, اکبرزاده , سمیه, حاج حیدری , زهره, کاشی , زهرا,

Background and Purpose: Lipodystrophy is potentially a clinical adverse effect, associated with insulin therapy and is believed that usage of human recombinant insulin’s is associated with decreasing prevalence of Lipodystrophy. The objective of this study was to determine the prevalence of insulin induced Lipodystrophy, among diabetic out-patients referred to Imam Khomeini Hospital, in Sari ...

2014
Paula Freitas Davide Carvalho Ana Cristina Santos António José Madureira Esteban Martinez Jorge Pereira António Sarmento José Luís Medina

BACKGROUND HIV-infected patients may be at increased risk of cardiovascular (CV) events, and lipodystrophy is generally associated with proatherogenic metabolic disturbances. Carotid intima-media thickness (cIMT) has been used as a surrogate marker for atherosclerosis and it has been shown to be an independent risk factor for CV disease. Our objective was to evaluate cIMT in HIV-infected patien...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2007
Kimberly M Szymanski Derk Binns René Bartz Nick V Grishin Wei-Ping Li Anil K Agarwal Abhimanyu Garg Richard G W Anderson Joel M Goodman

Lipodystrophy is a disorder characterized by a loss of adipose tissue often accompanied by severe hypertriglyceridemia, insulin resistance, diabetes, and fatty liver. It can be inherited or acquired. The most severe inherited form is Berardinelli-Seip Congenital Lipodystrophy Type 2, associated with mutations in the BSCL2 gene. BSCL2 encodes seipin, the function of which has been entirely unkno...

Journal: :European journal of endocrinology 2010
Jacques Beltrand Najiba Lahlou Tifenn Le Charpentier Guy Sebag Sofia Leka Michel Polak Nadia Tubiana-Rufi Didier Lacombe Marc de Kerdanet Frederic Huet Jean-Jacques Robert Didier Chevenne Pierre Gressens Claire Lévy-Marchal

CONTEXT Recently, in a 4-month proof-of-concept trial, beneficial metabolic effects were reported in non-diabetic children with Berardinelli-Seip congenital lipodystrophy (BSCL); this information prompted us to hypothesize that long-term leptin-replacement therapy might improve or reverse the early complications of the disease in these patients. PATIENTS AND METHODS A 28-month trial was imple...

Journal: :Journal of the College of Physicians and Surgeons Pakistan 2020

Journal: :IOSR Journal of Dental and Medical Sciences 2013

2017
Jing Chen Taizhong Hu

The concept of generalized order statistics (GOSs) was introduced as a unified approach to a variety of models of ordered random variables. The purpose of this paper is to investigate conditions on the underlying distribution functions and the parameters on which GOSs are based, to establish Shaked-Shanthikumar multivariate dispersive ordering of GOSs from one sample and Khaledi-Kochar multivar...

Journal: :International journal of epidemiology 2009
Karen Levy Alan E Hubbard Joseph N S Eisenberg

BACKGROUND To date little conclusive evidence exists on the seasonality of rotavirus incidence in the tropics. We present a systematic review and meta-analysis on the seasonal epidemiology of rotavirus in the tropics, including 26 studies reporting continuous monthly rotavirus incidence for which corresponding climatological data was available. METHODS Using linear regression models that acco...

2012
Sanjay Mishra Varun Joshi Nitin Bhardwaj N. Bhardwaj

The aim of this paper is to introduce and study the new class of sets called gprw-closed sets. This new class of sets lies between the class of regular weakly closed (briefly rw-closed) sets and the class of generalized pre regular closed (briefly gpr-closed) sets. And also we study the fundamental properties of this class of sets. Mathematics Subject Classification: 54A05

2014
Alan Harper Manish Wadhwa

This paper examines the price volatility in the silver spot (cash) market. A host of Generalized Autoregressive Conditional Heteroskedasticity (GARCH) models are used to analyze and gain a better understanding of the volatility of silver prices. We find the TGARCH (1,1) model indicates that both positive and negative shocks do not have a significant effect on volatility in the silver spot marke...

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