نتایج جستجو برای: computational methods
تعداد نتایج: 2080466 فیلتر نتایج به سال:
Statistical authorship attribution has a long history, culminating in the use of modern machine learning classification methods. Nevertheless, most of this work suffers from the limitation of assuming a small closed set of candidate authors and essentially unlimited training text for each. Real-life authorship attribution problems, however, typically fall short of this ideal. Thus, following de...
Metabolism is the system of chemical reactions sustaining life in the cells of living organisms. It is responsible for cellular processes that break down nutrients for energy and produce building blocks for necessary molecules. The study of metabolism is vital to many disciplines in medicine and pharmacy. Chemical reactions operate on small molecules called metabolites, which form the core of m...
We propose a vector space approach for relighting a Lambertian convex object with distant light source, whose crucial task is the decomposition of the reflectance function into albedos (or reflection coefficients) and lightings based on a set of images of the same object and its 3-D model. Making use of the fact that reflectance functions are well approximated by a low-dimensional linear subspa...
Phylogenetics is the study of relationship among species or genes with the combination of molecular biology and mathematics. Most of the present phylogenetic analysis softwares and algorithms have limitations of low accuracy, restricting assumptions on size of the dataset, high time complexity, complex results which are difficult to interpret and several others which inhibits their widespread u...
We discuss how a theoretical synthetic biology research programme may liberate empiricism in biological sciences beyond the unaided human brain. Because synthetic biological systems are relatively small and largely independent of evolutionary contexts, they can be represented with mathematical models strongly founded on first principles of molecular biology and laws of statistical thermodynamic...
A large number of computational problems and physical phenomena involve the motion of interfaces separating two or more regions. These can include problems in such areas as fluid mechanics, combustion, materials science, meteorology, and computer vision. In these problems, challenging issues often involve interfaces that change topology, form sharp corners and singularities, depend on delicate ...
Optical mapping and newer genome mapping technologies based on nicking enzymes provide low resolution but long-range genomic information. The optical mapping technique has been successfully used for assessing the quality of genome assemblies and for detecting large-scale structural variants and rearrangements that cannot be detected using current paired end sequencing protocols. Here, we review...
For a Boolean network we consider asynchronous updates and define the exclusive asynchronous basin of attraction for any steady state or cyclic attractor. An algorithm based on commutative algebra is presented to compute the exclusive basin. Finally its use for targeting desirable attractors by selective intervention on network nodes is illustrated with two examples, one cell signalling network...
Biomedical imaging represents a practical and conceptual revolution in the applied sciences of the last thirty years. Two basic ingredients permitted such a breakthrough: the technological development of hardware for the collection of detailed information on the organ under investigation in a less and less invasive fashion; the formulation and application of sophisticated mathematical tools for...
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