We synthesized an indolium–coumarin dyad (1) and its derivatives with –Cl (2), –N(CH3)2 (3), or –NO2 (4) substituent, and used them for fluorometric detection of cyanide anions (CN(-)) in aqueous media. All of the dyads exhibit fluorescence enhancement by CN(-) via a nucleophilic interaction of CN(-) with the indolium carbon atoms. Their fluorescence response and selectivity to CN(-), however, ...

The study of five-fold (P even, T odd) correlation in the interaction of slow polarized neutrons with aligned nuclei is a possible way of testing the time reversal invariance due to the expected enhancement of T violating effects in compound resonances. Possible nuclear targets are discussed which can be aligned both dynamically as well as by the ”brute force” method at low temperature. A stati...

Activation of brain alpha7 nicotinic acetylcholine receptors (alpha7 nAChRs) has broad therapeutic potential in CNS diseases related to cognitive dysfunction, including Alzheimer's disease and schizophrenia. In contrast to direct agonist activation, positive allosteric modulation of alpha7 nAChRs would deliver the clinically validated benefits of allosterism to these indications. We have genera...

synthesis and characterization of 6-(hydroxymethyl)-14, 16-dimethyl-13, 14, 16, 17-tetrahydro-6h-13, 17-epiminodibenzo [e, l] [1, 4] dioxacyclotridecin-15 (7h)-oneabstractnew 6-(hydroxymethyl)-14, 16-dimethyl-13, 14, 16, 17-tetrahydro-6h-13, 17-epiminodibenzo [e, l] [1, 4] dioxacyclotridecin-15 (7h)-one (2a) was synthesized in good yield by the petrenko–kritchenko reaction of 2, 2'-((3-hydroxyp...

learning vocabulary constitutes a crucial step in language learning. amongst different word categories, compound words have failed to attract the attention they deserve. this led us to conduct a study trying to pinpoint the difficulties learning these words and to suggest some techniques facilitating their acquisition. to that effect, a questionnaire as well as a vocabu-lary test were given to ...

This work presents an energy, exergy, and environmental evaluation of a novel compound PV/T (photovoltaic thermal) waste heat driven ejector-heat pump system for simultaneous data center cooling recovery district heating networks. The uses with evaporative-condenser as driving force ejector while exploiting the generated electric power to operate compressor pumps. vapor compression assessed sev...

KATP channels regulate insulin secretion by coupling β-cell metabolism to membrane excitability. These channels are comprised of a pore-forming Kir6.2 tetramer which is enveloped by four regulatory SUR1 subunits. ATP acts on Kir6.2 to stabilize the channel closed state while ADP (coordinated with Mg(2+)) activates channels via the SUR1 domains. Aberrations in nucleotide-binding or in coupling b...

The ZrSiS family of compounds hosts various exotic quantum phenomena due to the presence both topological nonsymmorphic Dirac fermions and nodal-line fermions. In this material family, LnSbTe (Ln= lanthanide) are particularly interesting owing intrinsic magnetism from magnetic Ln which leads new properties states. work, authors focus on previously unexplored compound SmSbTe. studies reveal a ra...

Abstract The IV–V groups binary compound germanium arsenide (GeAs) is a semiconductor that can be easily exfoliated in very thin nanosheets and characterized by band gap ranging from 0.6 eV (bulk form) up to 2.1 (monolayer). We investigate the field emission characteristics of multilayer GeAs means tip-anode setup, where nanomanipulated W-tip positioned front emitting layer at nanometric distan...