Background: Dysregulation of LncRNA antisense non-coding RNA in the INK4 locus (ANRIL) expression is implicated in pathogenesis and disease progression of a variety of cancer types. However, the expression level of ANRIL in pediatric patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) has not been elucidated, yet. The present study is an attempt to evaluate the expression leve...

The editorial “Non-physician Clinicians in Sub-Saharan Africa and the Evolving Role of Physicians” by Eyal et al describes non-physician clinicians’ (NPC) need for mentorship and support from physicians. We emphasise the same need of support for front line generalist primary healthcare providers who carry out complex tasks yet may have an inadequate skill mix.

the radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. these changes are confirmed by results of some in-vivo s...

for the first time in the history of logic, abd al razzaq al-jili (d. 570/1174), in the treatise al-lame fi al-shakl al-rabe, dealt with the modal syllogisms of the fourth figure. previous to him, dinha, the priest, and ibn salah al-hamadani had discussed the non-modal moods of the fourth figure. jili’s treatise deals only with simple modalities and ignores the complex ones. his pupil, fakhr al...

One of the methods to enhance bio-accessibility of drugs like Acridone and its oxime is toform inclusion complexes with β-cyclodextrin. The formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. The aqueous phasesolubility studies reveal 1:1 stoichiometry between the compound and, β-cyclodextrin. The studyof thermodynamic parameters like ΔG,...

non-communicable disease continues to be an important public health problem in india, being responsible for a major proportion of mortality and morbidity. demographic changes, changes in the lifestyle along with increased rates of urbanization are the major reasons responsible for the tilt towards the non-communicable diseases. in india, there is no regular system for collecting data on non-com...

A number of studies in the network science literature have attempted to model the effect of network structure on cognitive state fluctuations in social networks. For the most part, these networks use highly simplified models of both cognitive state and social influence. In order to extend these studies and provide the basis for more complex network science simulations, a model of socially-media...

background: in addition to determining the exact tumor location and its geometric features, an increase of the effective tumor atomic number will enhances the chance in treating the tumoral cells under suitable radiation. in the present study, we assessed metrezoate-labeled gallium transmission in burkett lymphatic cells. materials and methods: human burkitt lymphatic cells were grown in cultur...