The affinity ligand quality of the triazine dye, cibacron blue, toward serum albumin has been well studied [64-68]. By immobilizing the ligand to a stationary phase, affinity separations can be performed in order to remove bulk albumin from serum samples. This decrease in albumin concentration may serve as a direct advantage for proteomics as large amounts of serum albumin hinder the study of l...

Patients with Parkinson's disease display impairments of postural control most particularly in active, challenging conditions. The objective of the present study was to analyze early signs of disease-related and also age-related impairments in mediolateral body extension and postural control. Fifty-five participants (18 Hoehn and Yahr stage 2 patients in the off-drug condition, 18 healthy elder...

Maximum specific growth rate (mu(max)) and lag time (lambda) were estimated from viable count and absorbance data and compared for different microorganisms, incubation systems and growth conditions. Data from 176 growth curves and 120 absorbance detection times of serially diluted cultures were evaluated using different mathematical growth models. Accurate estimates of mu(max) and lambda were o...

To characterize the behavior and robustness of cellular circuits with many unknown parameters is a major challenge for systems biology. Its difficulty rises exponentially with the number of circuit components. We here propose a novel analysis method to meet this challenge. Our method identifies the region of a high-dimensional parameter space where a circuit displays an experimentally observed ...

The main objective of this study was to analyse the distance covered and the activity profile that players presented at the FIFA World Cup in 2010. Complementarily, the distance covered by each team within the same competition was analysed. For the purposes of this study 443 players were analysed, of which 35 were goalkeepers, 84 were external defenders, 77 were central defenders, 182 were midf...

The effects of two food materials, γ-aminobutyric acid (GABA) produced by natural fermentation and Apocynum venetum leaf extract (AVLE), on the improvement of sleep were investigated in humans. The electroencephalogram (EEG) test revealed that oral administration of GABA (100 mg) and AVLE (50 mg) had beneficial effects on sleep. GABA shortened sleep latency by 5.3 min and AVLE increased non-rap...

For many years, β-arrestins have been known to be involved in G-protein-coupled receptor (GPCR) desensitization. However, β-arrestins belong to a family of proteins that act as multifunctional scaffolding proteins, in particular during trafficking of transmembrane receptors. The arrestin family comprises visual arrestins, β-arrestins and α-arrestins. In mammals, the functions of the α-arrestins...

INTRODUCTION Cervical cancer has long been known as a preventable disease. Yet it still is a prime women's health issue globally. In Malaysia, the current cervical cancer screening program, introduced in the 1960s, has been found to be unsuccessful in terms of Pap smear coverage. The aim of this study is to determine providers perceptives on the program and the feasibility of practicing an orga...

Clonal plasma cell disorders (PCD) including mostly monoclonal gammopathy of undeter‐ mined significance (MGUS) and multiple myeloma (MM) are characterised by expansion of abnormal (clonal) plasma cells (PCs) producing monoclonal protein (M-protein, MIG). Although multiparametric flow cytometry (MFC) allows identification and characterisation of these neoplastic PCs, this approach is used in ro...

Various recent developments in Collaborative Networks (CNs) attempt to model a number of aspects that are characterized by an inherent imprecision and incompleteness of information. In fact, collaborative networks are complex entities whose proper understanding, design, implementation, and management require the integration of different modeling perspectives and techniques. Perspectives related...