Complement system is a major effecter system of the innate immunity that bridges with adaptive immunity. The system consists of about 40 humoral and cell surface proteins that include zymogens, receptors and regulators. The zymogens get activated in a cascade fashion by antigen-antibody complex, antigen alone or by polymannans, respectively, by the classical, alternative and mannose binding lec...

The modern trend in complement research concerns the functionally relevant interactions of complement components and the biologic activities of the complement system. The pri mary interest of students of complement today centers on complement as a humoral effector system which constitutes an integral part of the immunologically competent organism. There exists only a secondary interest at prese...

The complement system is an essential element of the innate immune response that becomes activated upon recognition of molecular patterns associated with microorganisms, abnormal host cells, and modified molecules in the extracellular environment. The resulting proteolytic cascade tags the complement activator for elimination and elicits a pro-inflammatory response leading to recruitment and ac...

This paper assumes the cell formation problem as a distributed decision network. It proposes an approach based on application and extension of information theory concepts, in order to analyze informational complexity in an agent- based system, due to interdependence between agents. Based on this approach, new quantitative concepts and definitions are proposed in order to measure the amount of t...