0.1 The Model Consider material flowing among n compartments labeled 1, 2, · · · , n. Assume to begin that no material flows into any compartment from the external environment but that material can flow out of a compartment to the external environment and be lost. Material may flow between compartments. In Pharmacokinetics, the material is a drug, administered to the body, say orally, and the c...

Radioisotopes (particularly (22)Na, (24)Na, (42)K, and (86)Rb) have been used for many decades to trace the fluxes and accumulation of sodium and potassium ions in plant tissues. In this article, standard procedures for the tracing of ion fluxes are described, with emphasis on special problems encountered when examining K(+) and Na(+) transport under salinity conditions. We focus in particular ...

We report 12 patients with infiltrating muscular lipomas of the lower limbs all treated by wide resection. During follow-up averaging seven years, the tumour recurred in five patients. Our results and those reported by others suggest that, in order to avoid recurrence, this tumour, although benign, should be treated by total excision of the muscle or by compartmental resection. Hormonal imbalan...

We give an overview of the analysis of a new type of bursting (“ghostbursting”) seen in pyramidal cells of weakly electric fish. We start with the experimental observations and characterization of the bursting, describe a compartmental model of a pyramidal cell that undergoes ghostbursting and the development of a simplified yet realistic conductance–based model of this cell. This model then mo...

Abstract. A compartmental epidemic model, introduced by Gumel and Moghadas [1], is considered. The model incorporates a nonlinear incidence rate and an imperfect preventive vaccine given to susceptible individuals. A bifurcation analysis is performed by applying the bifurcation method introduced in [2], which is based on the use of the center manifold theory. Conditions ensuring the occurrence ...

BACKGROUND [11C]Befloxatone measures the density of the enzyme monoamine oxidase A (MAO-A) in the brain. MAO-A is responsible for the degradation of different neurotransmitters and is implicated in several neurologic and psychiatric illnesses. This study sought to estimate the distribution volume (VT) values of [11C]befloxatone in humans using an arterial input function. METHODS Seven healthy...