Menopausal hormone therapy use in breast cancer survivors is controversial, and clinical trials of this issue have proven diffi cult. Eight years ago, two separate randomized trials of this question were begun, but accrual diffi culties led to development of a merger with a joint analysis plans. In 2004 the trials were stopped early after an interim combined analysis of the pooled data found an...

arterial blood gas (abg) sampling is a painful procedure with no perfect technique for quelling the discomfort. an ideal local anesthesia should be rapid, easy to learn, inexpensive, and noninvasive. this study was aimed to compare pain levels from abg sampling performed with vapocoolant spray in comparison to placebo. we hypothesized that pretreatment with the vapocoolant would reduce the pain...

background: suicide prevention is one of the priorities in policies of iranian ministry of health and medical education (mhme). the suicide prevention program had two main parts of identifying and treatment of the depressed and suicide high risk individuals by primary health care (phc) network. the main aim of this study was to evaluate the results of integration of the program into phc network...

background and purpose: the goal of asthma therapy is to achieve clinical control and near normal lung functions. many patients with moderate persistent asthma fail to achieve this goal with a low dose of inhaled corticosteroid (ïçs) plus long-acting β2 agonist (lâbâ). ïn the present study, we have checked whether another controller medication (in the form of ginger capsule) add on to ïçslow do...

objective: to evaluate the potential advantages of imipenem/cilastatin in control of fever in neutro-penic hsct recipients.patients and method: in this single-center study, 111 consecutive febrile episodes in 104 neutropenic hsct recipients with a mean age of 26 years were randomized to treatment either with imipenem/cilastatin 1 g, iv, q8h or cefepime (our standard regimen) 2 g, iv, q8h. if fe...

mini abstract: this study is an extended follow up of the original trial study (nct00600197) that has been published in the clinical journal of pain. this trial aimed to explore if the proposed multidisciplinary program could improve quality of life and disability of the patients suffering from chronic low back up to 36 months.   methods and material: in this clinical randomized trial seventy p...

objective(s): the study objective was to assess the diagnostic performance of positron emission tomography (pet) for gliomas using the novel tracer 18f-fluciclovine (anti-[18f]facbc) and to evaluate the safety of this tracer in patients with clinically suspected gliomas.methods: anti-[18f]facbc was administered to 40 patients with clinically suspected high- or low-grade gliomas, followed by pet...

introduction: due to penetration of pathogenic bacteria into the periodontal tissues in moderate to severe periodontitis, the mechanical methods are not sufficient in these cases. therefore, administration of local/systemic antibiotic is recommended following mechanical root debridement. however, side effects of antibiotics such as microbial resistance and patient allergy led to development of ...

results fifty seven patients were assigned to receive peg and 52 patients received cfe. after 4weeks of medication, 86.5% of children in cfe group and 77.1% in peg group (rr = 1.121, ci95%:0.939 - 1.338) exited from the criteria of fc. all measurable criteria improved in both groups without any significant difference, except in the frequency of defecation that in cfe group (10.96 ± 5.7) was sig...

results there were significant differences between the groups in subjective labor pain scores (except vas 4) (p < 0.001). the duration of the phase one (3 cm dilatation to full dilatation) and phase two (full dilatation to birth) in the acupressure group was shorter than the control group (phase one, 225 min and 320 min, respectively; phase two, 15 min and 20 min, respectively; both p < 0.001)....