Disc Degeneration: Spondylosis (Spondylosis Deformans) is a general term used for age-related changes to the disc. This includes disc dessication, bulging and marginal osteophyte. Disc degeneration (Intervertebral osteochondrosis) (Resnick) is characterized by disorganization and dessication of the nucleus pulposis and by disc space narrowing. With loss of disc space height there is annular bul...

PURPOSE To determine whether topographical measurements of the parapapillary region analyzed by machine learning classifiers can detect early to moderate glaucoma better than similarly processed measurements obtained within the disc margin and to improve methods for optimization of machine learning classifier feature selection. METHODS One eye of each of 95 patients with early to moderate gla...

Results are presented of spectroscopic emission and absorption line observations along the major axis of the Sb galaxy NGC 7331. The kinematics of the ionized gas and stellar component are derived, being regular and symmetric with respect to the centre of the galaxy. Contrary to what may be expected, for R <∼ 40′′ the emission line gas appears to rotate slower than the stars. A likely explanati...

Response to editorial regarding a novel surgical treatment option in which posterior dynamic stabilization is used to correct coronal plane tilt of a lumbar total disc replacement We recently described a novel surgical treatment option in which posterior dynamic stabilization (PDS) is used to correct coronal plane tilt of a lumbar total disc replacement (TDR). 1 Clinical and radiographic outcom...

INTRODUCTION Varied definitions of disc pathology exist in the literature. Magnetic Resonance Imaging (MRI) classification systems incorporate several qualitative features including disc appearance, the distinction between the nucleus and the annulus, signal intensity and intervertebral disc height. The lack of a continuous measure has made it difficult to sensitively examine degenerative disc ...

PURPOSE To describe optic disc variables assessed by evaluation of clinical optic disc photographs and to compare sensitivity and specificity of these optic disc parameters in identifying patients with ocular hypertension who have nerve fiber layer defects and normal visual fields and patients with visual field defects. METHODS The study included 500 normal subjects, 132 patients with ocular ...

Medical imaging is the process of creating visual representations of the interior portion of a human body for clinical analysis. Medical imaging reveals the internal structures hidden by the skin and bones, as well as to diagnose and treat disease. It also helps in identifying the abnormalities. Medical imaging technology helps doctors to see the interior portions of the human body and made eas...

Background & Aim: Low back pain is the most debilitating condition, and can lead to decreased physical function, compromised quality&nbsp;of life, and psychological distress. Several studies have been conducted to recognize the risk factors of low back pain, but despite of&nbsp;strong relationship between obesity and low back pain, the underlying mechanisms are unclear. The aim of this study wa...

STUDY DESIGN In vitro study to develop an intervertebral disc degeneration organ culture model, using coccygeal bovine intervertebral discs (IVDs) and injection of proteolytic enzymes MMP-3, ADAMTS-4, and HTRA1. OBJECTIVE This study aimed to develop an in vitro model of enzyme-mediated intervertebral disc degeneration to mimic the clinical outcome in humans for investigation of therapeutic tr...