نتایج جستجو برای: colorectal cancer
تعداد نتایج: 925796 فیلتر نتایج به سال:
Background and Objectives: Involvement of lymph nodes is an important prognostic factor in the most cancers, including colorectal cancer. In the recent years, invasion to blood and lymphatic vessels has been shown to predict involvement of lymph nodes and the number of involved nodes has been less studied issue. The aim of this study was determination of the relationship between the size of col...
Background: Colorectal cancer is one of the most common types of cancer and the cause of death of a large number of patients and requires investigating the causes of the disease and adopting targeted therapies. Considering the diagnostic, therapeutic, and prognostic significance of genetic markers, in the present study BRAF-V600E gene mutation was evaluated in tissue samples of colorectal cance...
Background and purpose: Colorectal cancer is the most common gastrointestinal cancer throughout the world. Knowledge about the disease incidence and its changes over time can be useful in planning for the prevention and cause detection, therefore this study aimed at investigating the incidence of gastric cancer in Iran. Materials and methods: This study was a reanalysis of existing data. We us...
background: transcriptional silencing of tumor suppressor genes and tumor related genes like gstp1 by methylation of promotor region cpg island is believed to be an important mechanism in tumorigenesis. the gstp1 gene encodes the enzyme glutathione s-transferase pi which defends the cells against oxidative damage and electrophilic carcinogens. methods: to gain insight into the role of epigeneti...
Background and Objectives: Marine algae are one of the natural resources which produce a wide range of new secondary metabolites with various biological activities such as antitumor and anticancer properties. The present study was conducted in order to evaluate the invitro cytotoxic effect of marine algae Gelidiella acerosa organic extracts against breast (MCF-7) and colorectal (HT-29) ca...
results methylation in at least one gene was reported about 93.8%. the methylation of sfrp2 was reported in 39 out of the 48 subjects (81.2%) whereas methylation of mgmt was observed in 32 subjects (66.6%). conclusions the current study results showed that methylation of sfrp2 and mgmt play an important role in polyp formation. materials and methods forty eight tissue samples of polyp and adeno...
Abstract Background: Colorectal cancer is one of the most common cancers worldwide. It is the third common cancer and the second leading cause of death from cancers in the developed countries. First degree relatives of colorectal cancer patient have a 2-3 fold higher risk to develop disease. Planning for Prevention from disease at this group needs to review their current needs and assess the...
Background and Objective : Lymphovascular involvement is the main and most important prognostic factor in colorectal cancer. This study aimed to evaluate the relationship of morphological differentiation and lymph/vascular involvement. Materials and Methods: In this cross-sectional study, the pathological results of 52 colectomy patients between 2006 and 2011 in Emam-Reza and Be’sat Hospita...
background: matrix metalloproteinases comprise a family of enzyme degrade components of extra cellular matrix. there are single nucleotide polymorphisms in the promoter regions of several genes with ability to influence cancer susceptibility. the aim of this study was to analyze association between mmp 3 promoter polymorphisms and colorectal cancer occurrence and progression. materials and meth...
Colorectal cancer is very rare in children. Therefore, the diagnosis generally established at advanced disease. This a presentation of two cases colorectal treated Habib Bourguiba Hospital University.
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